Wednesday, August 29, 2018

Bilateral Lumbar Hernias - A Case Report and An Overview of the Current Literature by Mina Cheng in BJSTR

Abstract

Primary lumbar hernia is a rare clinical entity. So far, around 300 cases have been described in the literature and almost all of them describe repair for unilateral hernias. We present a case of bilateral primary lumbar hernia repair at our institution.



Oral Medicine: The Awareness of Patients Using Steroid Inhalers on the Increased Risk of Oral Candidosis: A Service Evaluation by Saleh Nasser Aldallal in BJSTR

Abstract

Objective: To perform an evaluation of the current practice of informing patients on steroid inhalers of the increased risk of oral candidosis (thrush) as a side effect of using the inhaler.
Method: This is a service evaluation in the form of a survey distributed to patients attending the respiratory medicine outpatient clinic at the Manchester Royal Infirmary (MRI).
Results: The evaluation shows that the majority of patients are not informed of the risk associated with commonly prescribed steroid inhalers, and they feel that it is the responsibility of the doctors to warn them about this side effect. Very few patients received advice from their dentist on this matter.
Conclusion: All healthcare professionals are responsible for the well-being of their patients. Dentist should play active role in advising patients on the oral side effects associated with the use of steroid inhalers.



Actinomycetes as Tools for Biotransformations of Lignans by Suzan Pantaroto de Vasconcellos in BJSTR

Abstract

The current demands for novel and sustainable biotechnological processes, including new microbial enzymes with industrial potential are constantly required. As a form to address the growing need for industrially relevant enzymes, functional screenings of microorganisms and/or (meta)genome mining techniques have emerged as powerful strategies for the identification of promising enzymes to novel or improved industrial processes [1]. Once enzymes have been well characterized, they can be produced, studied, and engineered about their biocatalytic, including possible synergistic activities in multiple protein cocktails. Currently, there is an increased interest in exploring and exploiting microbial enzymes for selective degradation of plant biomass. The efforts are concentrated on the bioconversion of lingo-cellulosic material. While ample enzymes are nowadays available for the degradation and modification of the polysaccharide content of plant biomass, there is a need for effective lignin degrading enzymes.




Proteomics - The Future of Periodontal Diagnostics by Nisha KJ in BJSTR

Abstract

Recent advances of proteomic meth¬odologies have opened new opportunities to obtain relevant information on normal and abnormal processes occurring in the human body. Identifying unique patterns of protein expression, or biomarkers, associated with specific diseases is one of the most promising areas of clinical proteomics. Advances in proteomic technologies have enabled comprehensive profiling of protein expression in cells, tissue, and body fluids. The use of proteins as biomarkers for periodontal disease has been the focus of researchers over the last few years. Unfortunately, many single protein biomarkers have proven to be unreliable. Developing new diagnostic tests that can simultaneously analyze the expression of multiple proteins may enable early detection, targeted preventive measures and individualized therapeutic intervention of periodontal diseases. This review discusses the main proteomic techniques and their potential applications in the field of periodontal diagnostics.



Evolution and Epidemiology of Antimicrobial Resistance: Staphylococcus aureus by Sunil Pandey in BJSTR

Abstract

Staphylococcus aureus is a potentially pathogenic bacterium that causes a wide range of diseases. These are causing different infections and resistance mechanism due to of its wide virulence factors. The increase in the resistance of this virulent pathogen to antibiotic, day by day increases as a nosocomial infection is a major health concern. The main resistance phenotype associated with the S. aureus in hospital is methicillin resistance followed by vancomycin resistance. Resistance to methicillin and other b-lactam antibiotics is produced by the mecA gene, which is located on a portable genetic element, the Staphylococcal Cassette Chromosome mec (SCCmec). Center for disease control and prevention (CDC) approximates 80,461 hostile Methicillin resistance staphylococcal (MRSA) infections and 11,285 associated deaths occurred in 2011. Methicillin resistance in hospital acquired infections in S. aureus isolates has been increasing intensely in United States and occurring resistance to other antibacterial compounds. However, the role of evolutionary change in the pathogen throughout the development from bearing to disease is not completely understood. So, for this high throughout genome sequencing project need to be done to identify the genotypic character. To reduce these resistances more effective infection control, developing the new and improved antibiotic, developing vaccines, monitoring the trends in resistance, promoting interventions, conducting research are crucial. This review labels the latest molecular evolution of MRSA, different methods used to investigate the epidemiology, different risk factor associated with it and the structure of gene.





Juxtacortical Chondromyxoid Fibroma of Tibia by Mehrdad Bahrabadi in BJSTR

Abstract

Introduction: Chondromyxoid fibroma, CMF, is the least common benign cartilaginous tumor composed of chondroid and myxoid matrix. It is usually located eccentrically in distal femur or proximal tibia metaphysis. Juxtacortical Chondromyxoid fibroma which may be seen in unusual places such as intracortical, or sub periosteallocations is very unusual.
Case report: A 16-year-old boy presented to us with a mildly painful distal tibial mass for one year. Imaging studies showed a protruded mixed radio-opaque, radio lucent lesion at posterior surface of distal tibial metaphysis, without soft tissue involvement. A biopsy was performed which showed Chondromyxoid fibroma. Curettage and bone grafting was done as the therapeutic modality.
Conclusion: Chondromyxoid fibroma is usually not considered in the differential diagnosis of a painful, superficial lesion on a long bone. Other tumors such as periosteal chondroma, parosteal or periosteal osteosarcoma, parostealmyxoma, sub periosteal ganglion cyst, or periosteal osteoid osteoma are usually considered. Our case along with similar cases has proved that Juxtacortical CMF should be included in the differential diagnosis of a surface bony lesion.



The Use of Barbed Suture for Wound Closure in Hip and Knee Arthroplasty by Olga Solovyova in BJSTR

Abstract

The increasing number of total joint arthroplasties done on an annual basis, now over one million, along with evolving reimbursement strategies, has helped drive the need for more efficient performance of these cases [1]. This increased the demand for efficiency has led to pursuit of faster, more effective, safer, and cheaper surgical strategies. Soft tissue management is an integral part of total joint arthroplasty and its outcomes. Poor soft tissue handling can lead to dehiscence, infection, and unsightly scars. One of the more recent techniques in wound closure is the use of running barbed suture. The presence of either uni or bidirectional barbs eliminates the need for knots, potentially decreasing the time needed for closure and the number of sutures required and eliminating the gaps between sutures in the layer being closed. This paper summarizes the existing literature pertaining to the use of these suture constructs in total joint arthroplasty.




Adverse Health Consequences of Dietary Advanced Glycation End Products (ages) and Inhibitory Effects of Natural Ingredients on Ages by Qingrong Huang in BJSTR

Abstract

Dietary advanced glycation end products (AGEs) may result in various adverse health consequences, such as inflammation, cancer, liver diseases, obesity, cardiovascular diseases, diabetes, proteostatis impairment and memory decline. Natural ingredients may be a promising strategy to inhibit AGEs generation and ameliorate health risks of AGEs. The mechanisms involved in inhibition of AGEs with use of natural ingredients include antioxidant activity, reactive carbonyl trapping, and suppressing pathways of RAGE (receptor of advanced glycation end product), MAPK (mitogen-activated protein kinases) and NF-κB (nuclear factor-kappa B).This mini review summarizes the present understanding of the adverse impact of AGEs on health and the inhibitory effect of natural ingredients on AGEs.



How Does Stathmin Destabilize Microtubules? A Root of Consciousness and Alzheimer’s Disease by Majid Monajjemi in BJSTR

Abstract

Alzheimer’s disease due to dementia and the memory brain that might be related to the microtubules disorder interrupt daily life. Alzheimer’s is a brain disease that causes a slow decline in concentrations, memory, thinking and reasoning skills. By this research we exhibited the important rules of stathmin destabilize microtubules as a root of this problem in view point of chemical molecular engineering.



Natural Edible Oils: Comparative Health Aspects Of Sesame, Coconut, Mustard (Rape Seed) and Groundnut (Peanut) A Biomedical Approach by Arun Kumar Sharma in BJSTR

Abstract

Fats and Oils are one of the large groups of organic compounds which are of great importance in the food. We eat oils because they are readily digested and utilized in the body. The chief contribution of fats and other lipids to the diet is their energy value and also satiety value. Fats and other lipids also contribute essential fatty acids to the diet which body cannot synthesized .Fats are also act as solvents for the fat soluble vitamins such as A,D,E and K and the protamine At, the Carotene. The Fats and lipids are therefore important in the diet for number of reasons. Edible oils have significant role in diet all around the world especially in India as Indian culture is based on idealism of well beings of all creatures of the earth.




Biomarkers and the Future of Pediatric Gastroenterology by Lindsay M. Moye in BJSTR

Abstract

Biomarker discovery in the field of pediatric gastroenterology is necessary so that clinicians can use objective, non-invasive ways to screen for a disease in its preclinical stage, measure disease severity or monitor response to a particular treatment. The utilization of high-throughput analyses, such as with proteomics and metabolomics, allows researchers to quickly investigate numerous methodologies and generate large datasets, while only requiring small quantities of the biological specimen.



Cypriot Patients with Inflammatory Bowel Disease and Quality Of Life by Maria Tsoukka in BJSTR

Abstract

The aim of the present study was to investigate the Quality of Life of patients suffering from IBD and the factors that might be affecting it. The idiopathic Inflammatory Bowel Diseases (IBD) are chronic nosological entities negatively affecting the Quality Of Life of patients suffering from IBD in relation to the total population. Evaluating their Quality of Life is the basic constitution for evaluating their needs and for designing the suitable health care system to be provided. In the province of Larnaca the SIBDQ questionnaire translated in the Greek language was used to evaluate 100 patients suffering from Ulcerative Colitis and Crohn’s disease. We studied the Quality of Life as a dependent variable correlated with the independent variables that are the demographic and general characteristics of this patient group.




High Risk Pregnancy by Surya Malik in BJSTR

Abstract

“Let every mother and child to be counted”
Motherhood is a natural phenomenon, but safe motherhood is fraught with many complications related to of pregnancy and child birth. A “high risk pregnancy”(HRP) is one in which the maternal environment or past reproductive performance presents a significant risk to fetal wellbeing , such as premature birth, small for date infant, full term with low reservoir or still births and early neonatal deaths. Identification of patients at risk for these complicated pregnancies with poor outcome is fundamental to antenatal care. A woman is considered to have a high risk pregnancy when health concerns exist that may threaten the natural course of the development or birth of the baby, or that pose a risk to the mother. In such cases the mother may need special care, more investigations and possibly medication to ensure that she can carry the baby safely through to delivery. While pregnancy is a natural condition, it can be complicated even in healthy woman’s body because of changes in blood volume, hormone balance, pressure, the physical burden of pregnancy etc. Underlying medical conditions can add even more stress while complications caused by pregnancy itself (such as preeclampsia or gestational diabetes) can turn a normal pregnancy into a high risk pregnancy. A pre-pregnancy visit with a health care provider is especially important for a woman who has a medical problem.




High Risk Pregnancy by Surya Malik in BJSTR

Crystal Structure and Pharmacological Importance of Benzimidazoles and Their Derivatives by Mohamed Ziaulla in BJSTR

Abstract

Benzimidazoles and their derivatives exhibit a number of important pharmacological properties, such as antihistaminic [1], anti-ulcerative [2], anti allergic [3], and antipyretic [4]. In addition, benzimidazole derivatives are effective against the human cytomegalovirus (HCMV) [5] and are also efficient selective neuropeptide Y Y1 receptor antagonists [6]. We report here in the Crystal structure of 2-(4-(methylthio) phenyl)-1H-benzo[d] imidazole (1) and 2-(4-Methylsulfanylphenyl)-1Hbenzimidazol-3- ium bromide (2).



Invasive Pneumococcal Disease in HIV-Infected Patient - Case Presentation by Olivia-Simona Dorneanu in BJSTR

Abstract

Due to important structural changes occurring in the immune system exposed to HIV, the risk of sepsis in HIV-positive patients increases proportionally to the duration of this exposure as well as the presence/evolution of other debilitating pathologies. Streptococcus pneumoniae is one of the main causes of invasive infections in HIV-infected patients, and the risk of severe pneumococcal disease is several times higher than the general population. We present the case of an invasive pneumococcal disease in a HIV-infected patient with a strain resistant to third generation cephalosporines.




Aligning Pathology Assessment in a Learner-Cantered Undergraduate Medical Curriculum by Neelam Doshi in BJSTR

Abstract

Introduction : The Bond Medical Program delivers pathology in the preclinical years through interactive learning. Assessment for learning demandsfit-for-purpose assessmentthat aligns with the curriculum. In Year 2 of the medical curriculum, clinical pathology is assessed through a series of written and an integrated practical assessment (IPA) examination. The IPA is a practical examination held in a laboratory which permits the use of multi-media. The traditional written paper examines the theoretical aspect of pathology while the IPA assesses the observational skill and three dimensional application of pathophysiology to disease processes.
Objectives : To determine whether a difference exists in student performance on pathology questions between the IPA and a written examination.
Methods : Year 2 undergraduate medical students write a 50-station IPA, followed by a 50-question written paper. A comparison of performance between the written assessment and the IPA is undertaken and correlated using Pearson correlation coefficient.
Results : A positive Pearson’s correlation coefficient of percentage scores (r=0.68, significant at > 0.01) between the written and IPA suggests a strong association between the two assessment methods.
Conclusion : Students’ scores in the IPA and the written assessment correlate well which suggest either could be used to predict students’ performance in pathology. The IPA enables students to connect the basic sciences with clinical sciences, thus aligning our learner centred pathology curriculum with the assessment tools.



Assessment of Knowledge Attitude and Practice towards Solid and Liquid Waste Management among Addis and Kometa Kebele Community Mizan-Aman Town, Bench – Maji Zone, Snnpr, South Waste Ethiopia, 2017 by Tesfaye Abera in BJSTR

Abstract

Background: Waste is defined as unwanted remains, residues discarded, and material or by products which are no longer required by the initial user. These materials are by-products of human activities such as process of preparation, manufacture, packing, repacking, unpacking, construction, renovation of structures and mining operations. Almost any substance that is discarded is designated as waste, but it may also be considered as a potential resource. Virtually everything in the “waste stream” has residual value for someone or some business in the community. Waste can serve as valuable resources as ground cover to reduce erosion, fertilizer to nourish the crops. KAP studies investigate the knowledge attitude and practice of respondents on the particular subject of interest. KAP studies tell us what people know about certain things, how they feel, and how they behave. The knowledge possessed by a community refers to their understanding of waste generation, description and recycling in this context. Attitude refers to their feeling toward waste separation, collection as well as recycling. Practice refers to the way in which they demonstrate their knowledge and attitude throw their actions.
Objective: Assessment of the knowledge, attitude and practice of Addis and Kometa kebele community towards waste disposal management in South West Ethiopia, 2017.
Methodology: A descriptive cross-sectional design and systematic sampling technique was used to assess liquid and solid waste disposal management in Mizan-Aman Town community. Data was collected from 392 selected samples and was tallied manually, processed and analyzed in a line of its objective by using manual tally and table of frequency. Data quality was assured by performing pre-test to evaluate the appropriateness of data collection instrument.
Result: The finding of this study showed that majority 84% of the respondents were females, regarding their ethnicity 35.5% were Bench, also majority of the participants(87.1%) were married with regard to their religion (47%) were Orthodox, on the other hand 48.6% of the respondents were the age between 21-30. Furthermore, the study showed that 81.8% of the respondents have good knowledge, 77.5% of the participants showed positive attitude toward waste management as well as 76.9% of participants have good practice to ward waste management.
Conclusion and Recommendation: The finding of the study revealed that majority of Mizan-Aman town community have good level of knowledge, have positive attitude and showed good practice to ward waste management.
A. The Mizan-Aman town municipality was recommended to prepare pits/ditches in the town in sufficient quantity for solid waste disposal.
B. Mizan-Aman town community has best knowledge, positive attitude and good practice so Mizan-Aman Municipality, Addis and Kometa kebele administrators and health extension workers should do more to ensure the sustainability of this trend as well as to aware 100% of community.
C. Further detailed studies were recommended for intervention by using this high light for further interventions.



Genotoxic Effects on buccal Cells of Workers Exposed to Fogging Sprays during Fogging Operation by Normah Awang in BJSTR

 Abstract

Background: Genetic damage is one of the most fundamental causes of structural and functional changes in DNA. There are a great number of physical, chemical, and biological agents that, either directly or indirectly, damage the integrity of this macromolecule. Genetic damage may be caused by environmental exposure to genotoxins, radiations, chemicals, micronutrient deficiency, lifestyle factors, and genetic factors.
Methodology: Analysis of micronucleus in buccal cells is used to study the genotoxic effect on workers exposed to fogging sprays during fogging operation. In this study, buccal cells from 31 fogging workers and 24 office workers were collected. The former was the exposed group, while the latter was the control group. The respondents were also required to answer a questionnaire. DNA damage was scored by counting the frequency of micronucleus per 1,000 cells for each sample. Scoring was done by observing the formation of micronuclei after staining using acridine orange.
Results: The result showed that the frequency of micronucleus in the fogging workers was significantly higher than the office workers. Other factors affecting the formation of micronuclei, such as age, smoking status, and years of pesticide exposure, was also investigated in this study. The results proved that there was a significant difference in the frequency of micronucleus among the workers who smoked and workers who did not smoke in the exposed group. In contrast, there were no significant differences for the factors namely age and years of pesticide exposure. There was also a weak positive correlation between working period (years) with the frequency of micronucleus, with r2 = 0.387, p<0.05. Multiple linear regression test also suggested that smoking status and years of pesticide exposure can be the significant predictors for the frequency of micronucleus (p<0.05).
Conclusion: The genotoxic effect that occurs in fogging workers should be further assessed to improve their health and to maintain the safety at the workplace.



Practicing changing cases using ICG technology in Breast Reconstruction by Sanjay Warrier in BJSTR

Abstract

SPY Elite technology utilizes ICG angiography and is a method of intra-operative tissue perfusion assessment. In breast reconstructive surgery, knowledge of skin flap perfusion can assist intra-operative decision making. Altering the surgical plan accordingly can decrease the risk of ischemic complications. The current case series includes six mastectomy and complex reconstructive operative cases that utilized SPY Elite technology. The cases demonstrate how SPY Elite assessment led to changes in intra-operative decision making in a group of predominantly high risk patients.



Class Based Variable Importance for Medical Decision Making by Danielle Baghernejad in BJSTR

 Abstract

In this paper we explore variable importance within tree-based modeling, discussing its strengths and weaknesses with regard to medical inference and action ability. While variable importance is useful in understanding how strongly a variable influences a tree, it does not convey how variables relate to different classes of the target variable. Given that in the medical setting, both prediction and inference are important for successful machine learning, a new measure capturing variable importance with regards to classes is essential. A measure calculated from the paths of training instances through the tree is defined, and initial performance on benchmark datasets is explored.



Yak’s Biochemistry Contain the Factors that Make it Possible for Human Habitation on the Top of the World in Central Asia by Herbert W Ockerman in BJSTR

 Abstract

The yak (Bos grunniens) fills the role of nutrition, fuel, leather and transportation of goods for inhabitants of this harsh environment. In fact, if nature had not created this animal, human life would be almost impossible for an extended period of time in this area of the world. Yaks are a major source of livelihood of the people living in the high altitude, cold weather parts of this planet.



Effect of Ethanolic Extract of Different Parts of Plant (Annona Squamosa) on the Fertility of Male Rats by Veena B Kushwaha in BJSTR

Abstract

Plants, since ancient times, have been used globally across the civilizations as valuable, safe and natural agents of therapeutic, industrial and environmental utilities. From the inception of civilization, humans have relied on plants for their basic necessities like food, shelter, clothing, fuel and health. Of all the uses ascribed to the plants, the curative abilities of plants play an inevitable part as plants sometimes comprise sole source for healing ailments for some civilizations. Plants have also been explored for population control (Annona squamosa) is reported to posses various medicinal effects like insecticidal, antiovulatory and abortifacient. The present study therefore reports the effect of ethanolic effect of leaves, bark and seeds on the fructose level in testis, vas deferens and seminal vesicles, sperm count and sperm motility in rats. A significant decrease (p<0.05) was observed in the level of fructose in testis, vas deferens and seminal vesicle on exposure to the ethanolic extract of leaves, bark and seeds of plant (Annona squamosa) and a significant (p<0.05) decrease in sperm count and motility was also observed in the rats exposed to the extracts of plant in comparison to control rats. The decrease in fructose level, sperm count and motility was found to be time and dose dependent. Among the different parts of the plant, leaves, bark and seeds the effects were in the order leaf < bark< seed. The study clearly indicates plant extracts have potential to inhibit male fertility.




Ship Recycling Status in Bangladesh and Annual Reusable Material Output by Khandakar Akhter Hossain in BJSTR

Abstract

The fabric of a ship, whether of wood a century ago, or steel today has always had considerable value. Ship recycling is an engineering process [1] of dismantling obsolete ship to collect useable materials. One interesting point is that, the shipping industry is well ahead of other industries, such as the automotive and aviation sectors, in re-using some 85-98% of a ship by weight. On the other hand, even if ship recycling has been efficient in providing a ready supply of steel and other metals for re-use, there has been a cost in terms of lives lost and local environmental impact. The demolition of ships is widely associated with dangerous practices and pollution. Cutting apart big steel structures is a complex and hazardous business. And even though a high proportion by weight of the ship’s structure is re-usable, there are significant amounts of plastics, chemical product and other materials that should be handled carefully and appropriately. However, there are few dozen operational ship-recycling yards located along coastal belt at Chittagong of Bangladesh [2] comprehensively. This industry provide main source of steel, create huge employment [3] and generates large amounts of revenues for the government of Bangladesh. It is also contributing to the local shipbuilding industry.



Bacteria A Benefit Cell by Awatif Aljudaibi in BJSTR

Abstract

Before birth, microbiota does not exist in the human body, and microorganisms start to adapt in several locations in the body after birth. The microflora in the intestinal tract takes a long period to be formed. After they formed, human body get benefits from these microbiota and the important benefit the immune system supports, disposal of waste gastrointestinal, development metabolism and resistance the body against the pathogenic microorganisms [1-7].




Bacteria A Benefit Cell by Awatif Aljudaibi in BJSTR

Spontaneous Internal Drainage of Iatrogenic Oesophageal Perforation by Siba Senapati in BJSTR

 Abstract

Oesophageal perforation is a potentially fatal disease; however, with newer technologies many strategies are available to manage this. We present a case of a 60 year old woman with iatrogenic perforation of Zenker’s diverticulum and how she was managed.



Syringomyelia in the Thoracolumbar Spinal Cord of an African Wild Dog (Lycaon Pictus) by Jessica M Weeks BS in BJSTR

Abstract

A captive born neonatal African wild dog (Lycaon pictus) exhibited hind limb weakness and ataxia since the onset of ambulation. Initial examination at one month of age revealed postural reaction deficits in both hind legs and moderate muscle atrophy. After sustaining a bite wound to the head, the animal was reexamined at 87 days of age. A cerebrospinal fluid analysis showed a mild mononuclear pleocytosis. Magnetic resonance imaging indicated a large syrinx in the thoracolumbar spinal cord. The animal was subsequently euthanized and necropsy confirmed the presence of a 1.5 cm x 3 mm syrinx at the T13-L1 level of the spinal cord. This is the first report of syringomyelia in any nondomestic canid. Limited genetic diversity in the captive African wild dog population may contribute to increasing prevalence of rare congenital and inherited diseases, which could support strict breeding management in this species.



New Insight in Human Lactonase PON2 by Giuseppe Manco in BJSTR

Abstract

Mineral elements play a critical role in building body tissues and regulating numerous physiological processes. They are thus essential constituents of enzymes and hormones; regulate a variety of physiological processes, and are required for the growth and maintenance of tissues and bones. Living organisms (including plants, animals and microorganisms) store and transport metals so as to get appropriate concentration for later uses in physiological reactions as well as a means of protection against the toxic effects of the metals. This paper reviews the mineral contents of medicinal and stimulating plants in Ethiopia.




Mineral Contents of Selected Medicinal and Stimulating Plants in Ethiopia by Bhagwan Singh Chandravanshi in BJSTR

Abstract

Mineral elements play a critical role in building body tissues and regulating numerous physiological processes. They are thus essential constituents of enzymes and hormones; regulate a variety of physiological processes, and are required for the growth and maintenance of tissues and bones. Living organisms (including plants, animals and microorganisms) store and transport metals so as to get appropriate concentration for later uses in physiological reactions as well as a means of protection against the toxic effects of the metals. This paper reviews the mineral contents of medicinal and stimulating plants in Ethiopia.




Application of Radioimmunoassay for Livestock Fertility Management by Sukanta Mondal in BJSTR

Abstract

Reproductive performance is one of the important factors for determining the economics of livestock production. Reproduction is a complex luxurious process affected by environmental factors and involves a series of physiological processes and supported by endocrine system through release of various hormones A sound knowledge of reproductive functioning in terms of interplay of hypothalamic, gonadotropic and gonadal hormones, with synergistic and antagonistic influences from other hormones and factors involved in the regulation of various reproductive stages, accurate oestrus detection, timely pregnancy diagnosis and early detection of non-conceived stock can be expected to lead to an improvement of the reproductive efficiency. The different phases of reproductive cycle and pregnancy are regulated by intricate sequential events and interactions between hypothalamic releasing hormones, hormones secreted from the pituitary and sex steroids secreted by the ovary. Lack of integration or synchronization or endocrine imbalances at any phase of the sequence may result in reproductive failure. This paper focuses on use of various hormones for detection of estrus and early pregnancy in livestock.






Correlation of Reduced Glutathione with Brest Cancer Using High Performance Liquid Chromatography by Mufeed Jalil Ewadh in BJSTR

Abstract

Breast cancer (BC) is a type of malignancy appeared in breast tissue, occurs in both premenopausal and also in postmenopausal women’s. Glutathione (GSH) is a tripeptide that is found intracellularly in high concentration, being the most abundant low molecular mass thiol. A total of 80 patient with (BC) divided in two groups, first group (n=40) women with breast cancer without chemotherapy, second group (n= 40) women with breast cancer with chemotherapy. The control group (n= 40) apparently healthy women’s matched with patient group. Women with (BC) have a significant lower serum level of (GSH) than those who are not diseased and even than those who received chemotherapy (p˂ 0.05). So, this lead to a conclusion that; breast cancer women have low level of GSH and increased upon administration of chemotherapy. The objective of this study is to assess GSH status in women’s BC receiving chemotherapy treatment.



Healing and Prophylactic Efficacies of Topical Composite Herbal Medication on Overuse-induced Achilles Tendinosis

  Healing and Prophylactic Efficacies of Topical Composite Herbal Medication on Overuse-induced Achilles Tendinosis Introduction Tendinopath...