Abstract
The purpose of this paper is to examine adolescent depression
detection from a #clinical database of 63 #adolescents (29 depressed and
34
non-depressed) interacting with a parent. A range of spectral roll-off
parameters was investigated to observe an association of the #frequencyenergy relationship in relation to #depression. The spectral roll-off range
improved depression classification rates compared to the best
individual roll-off parameter. Further improvement was accomplished
using a 2-stage mRMR/SVM feature selection approach to optimize
a roll-off #parameters subset. The proposed optimized feature set reached
an average depression detection accuracy of 82.2% for males and
70.5% for females. More acoustic spectral features were investigated
including flux, centroid, entropy, formants and power spectral density
to
classify depression.
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Abstract
#Morphology of #filamentousfungi in submerged #fermentation has a huge
impact on product yield. In order to discover the genes related
with pellets formation, the method of insertion mutation by T-DNA was
employed to construct the #mutagenesis library of marine #Aspergillusniger. In this study, 125 positive transformants were identified by
detecting the expression of enhanced green fluorescence and one mutant
easier to pelletize was selected by flask-shaking test. The insertion
site of T-DNA, determined by hiTAIL-PCR, was located in the promoter of
plasma membrane ATPase gene. The mutant exhibited decreased production
of spores, weaker salt- and acid-tolerance and a broader range of
optimal growth temperature
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Abstract
#Counter-intuititvely, it is #socio-historical, #geographictraits, and
natural conditions which led to marijuana’s #stigmization as drug.
Besides,
its stigmization in U.S. is rather related with racialorign of its
introduction; it was first brought by black slaves and Mexican refugees
fleeing from
Mexico Revolution in 1910. Despite previous prevalence of its
consumption over tobacco, since 1920s the white’s racist fear and ant
sentiments
led to its prohibition. However, since late-2000s scientists began
revealing that marijuana’s defects had been hitherto exaggerated and
that its
harm is even less than that of alcohol-drink. Besides, the racist origin
of marijuana prohibition lately came into light, suppressing any #antimarijuana
stance as a strong ideological tool. As a result, by 2016 more than a
half of Americans consume or have consumed marijuana.
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Abstract
The importance of intermittent delta activity and periodic patterns
in the electroencephalogram has intrigued #neurophysiologists for
decades. The clinical interpretations varied from nonspecific to
suggested structural metabolic behavior, infectious and even #epilepsy
[1]. The
most frequent #clinical features were determined by #clinicalhistory of
children with intermittent rhythmic delta activity and periodic patterns
(January 2013-June 2017). Total 16 patients, Female 9 (56%). Periodic
patterns: 25% (n = 4) PLEDs, 13% (n = 2) BiPLEDs and 6% (n = 1)
GPEDs. Intermittent rhythmic delta activity: 50% (n = 8) FIRDAs and 6%
(n = 1) OIRDAs. The most frequent causes of PLEDs were infectious
and #tumoral in 12.5% (n = 2) respectively. Tumor causes were the most
frequent cause of FIRDAs 31% (n = 5), then neuroinfection12.5% (n = 2)
and vascular 6% (n = 1).
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Abstract
Background and Objectives: To determine the prevalence of and risk factors for cardiovascular abnormalities of #asymptomaticnewonset left bundle branch block (LBBB) in elective #noncardiacsurgery.
Methods: This study was a retrospective chart review about the
#preanestheticevaluation center at a medical center in southern Taiwan.
The charts of 87,185 patients who underwent elective noncardiac surgery
in were reviewed. Patients who showed LBBB in the preanesthetic
electrocardiogram were enrolled and analyzed. Patients with positive
findings in the preanesthetic cardiovascular examination were
categorized into the positive group, while the others were placed in the
negative group. Prevalence of asymptomatic new-onset LBBB, risk
factors for positive findings, and adverse #postoperative outcomes.
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Abstract
#Pyogenicgranuloma is thought to be an extreme tissue response to
trauma or local irritation. Hormonal changes also trigger the formation
of the lesion. Clinically, this lesion is usually found as single
nodules or vesicular papules with smooth or #lobular surfaces. They can
be seen
from a few #millimeters to a few centimeters at any size. It is known
that pyogenic granuloma occurs more frequently in the teeth (75% of all
cases). In this article, we presented a laser-assisted #surgicaltreatment of a #gingival pyogenic granuloma consisting of the right molar
region of
the mandible in a 22-year-old pregnant woman.
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Abstract
The #global threat posed by antibiotic resistance is well recognized,
but despite, guidelines, antibiotics continue to be over-prescribed
and frequently misused. One area where antibiotics may be used with
considerable less frequency is in the management of infected wounds,
particularly where the infection is localized and not systemic. This
paper presents the case for considering the use of octenidine-based
antiseptics for both wound care and whole-body decontamination, in order
to prevent wound infections as well as to treat already locally
infected wounds. A case report is presented which examines the
management of a superinfected wound without the use of systemic or local
antibiotics. Complete wound closure was achieved using a combination of
octenidine based products.
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Abstract
Heat shock protein 90 (Hsp90) is a molecular chaperone, indispensable
for the stability and function of several conditionally activated or
expressed signaling proteins. Hsp90 inhibitors can cause the
inactivation, #destabilization and eventual degradation of HSP90 client
proteins by
interacting predomently with a singular #molecular target. Hsp90 #inhibitors are unique in such a way that even though they are directed
towards
a specific molecular target, they simultaneously attenuate multiple
signaling pathways that frequently interact to promote cancer cell
survival.
HSP 90 #inhibitors displayed promising #antitumoractivity in #preclinicalmodel systems. The herbs containing alkannin (3) and shikonin (4) are
used in the treatment of measles, smallpox, sores, ulcers and wounds and
skin eruptions in traditional Chinese medicine (TCM).
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Abstract
#Pediatric dentistry is an age-defined specialty that provides
both primary and comprehensive preventive and #therapeutic oralhealth care for infants and children through adolescence, including
those with special health care needs. Pediatric care is actually a
#multidisciplinary treatment approach which include Rare diseases are a group of more than 5000 diseases that account
for 10% of #human disease [2-4]. In the last decades the attention
of several disciplines of medicine have been focused on rare
diseases; rare diseases are estimated to be 5000, and every week 5
new rare diseases are considered as new findings hence the number
of these diseases is enormously increasing.
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Abstract
The use of composite for posterior #teethrestoration competes with
amalgams, metallic and #ceramic inlays, in the important #deterioration cases. Its use is increasing and it’s becoming possible because of the
current progress of composite material technology and bonding evolution.
Even though the #dentists seem informed and able to achieve successfully
the direct composite technique, the use of composite restoration
with indirect or extra-oral method remains uncertain. In this article,
we will explore composite systems used at the laboratory for indirect
restoration and we will treat, step by step, the composite inlay
realization.
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Abstract
The oral effects of HIV and AIDS occur because of your weakened
immune system and the #medicines that kept under control. These effects
have also found in other people with weakened #immunesystems. Dry mouth
(xerostomia) because people with HIV have an increased risk of
cavities, dentist will provide a program to reduce the risk. This may
include fluoride varnishes applied in the dental office, toothpastes
that
add minerals to teeth and rinses that contain fluoride or reduce acid
(acidity of mouth) in the mouth. Patient education has an essential part
of
this program. Dry mouth has #xerostomia has a symptom of #HIVinfection but not something that would be used as a diagnostic tool. There are
many reasons if you have HIV, changes in mouth may reflect changes in
immune status. Dry mouth (xerostomia) has a common side effect of
medicines that may take for HIV/AIDS.
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Abstract
In Figure 1 the rectangular crossing point with slopes of AA1
and DB on the impenetrable horizontal basis of length of L is presented.
Water height in the top tail of Н, lower tail with water level
of Н2, having partially impenetrable vertical wall CD (screen), adjoins
a layer sole. If the working part of the crossing point CB (filter)
of width of H1 is flooded, H2>H1, an interval of seepage, usual for
dams, is absent. The upper bound of area of the movement is the
free surface of AD, coming to the #disproportionate CD, screen to
which there is a uniform #evaporation of #intensity ε (0 < ε < 1).
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Abstract
Gels or #hydrogels are described as the matrix of cross-linked
polymers. Hydrogels are naturally a part of the body in the form of
collagen,
gelatin, mucous, tear films, cartilage, vitreous humor, cornea, and
#tendon. Collagen, gelatin, and #nanofillers can be used to modify the
strength of
hydrogels. Use of biodegradable hydrogel scaffold is ideal for tissue
regeneration, where the scaffold degrades as the #tissueregeneration
occurs.
The hydrogel can be lone or composition of fundamental properties such
as edible, non-edible, #biodegradable, non-biodegradable, #injectable,
topical, natural, synthetic, physically crosslinked, chemically
cross-linked. During past three decades hydrogels due to various factors
such as
biodegradable, absorbent, tissue resemblance and easy use, have received
the enormous attention from researchers around the globe.
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Abstract
Populations are aging throughout the world. As people age,
their need for regular professional oral care and for home #oralhygiene
increases. Oral diseases have been linked to the increased
incidence of certain systemic #diseases and early mortality. Yet, the
provision for satisfactory oral care for the elderly is often lacking. This essay reviews the oral care needs of the elderly, the challenges
in providing such care to seniors that are home-bound or living in
assisted care facilities, and notes certain opportunities for raising
the standards of care. Greater understanding of the oral healthcare
needs of elderly in assisted care facilities is needed.
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Abstract
Clustered regularly interspaced short #palindromicrepeat (CRISPR) and
CRISPR associated protein 9 (Cas9) form a complex known as
CRISPR-Cas9, which is an efficient tool for gene editing that was
discovered through the study of bacterial defense mechanisms against
foreign #nucleic acids. This technology allows for the knock-out or knock-in of
specific DNA sequences. Therefore, CRISPR-Cas9 may provide a new
method to abrogate the effects of genes that lead to disease or
introduce genes that promote improvements in health. The powerful nature
of
these potential uses can be illustrated by considering the #geneticbases of #diseases such as cancer or #obesity. Clearly, there will be many
ethical
debates about the future of this technology to alter genetic function.
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Abstract
#Inflammatory bowel disease (IBD) is a chronic, relapsing, #idiopathic inflammation of the gastrointestinal tract characterizing chronic#colonic inflammation of GIT. This results from the interaction between
the various components of the mucosal immune system and the
#microenvironment. It is considered as an auto immune disease (AID)
involving various factors like immune dysregulation, genetic
predisposition,
dysbiosis of commensal flora and environmental factors. ATP-binding
cassette (ABC) #transporters are a large superfamily of #membrane proteins
with various functions and are also expressed on apical lining of
intestine. They utilize the energy from ATP hydrolysis for import and
export
of from ATP hydrolysis for import and export of substrates.
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Abstract
Introduction: Dual #Diagnosis is undoubtedly one of the most
important and particular problems that mental health services are
facing.
The common problem of all patients is that is entering in #PsychiatricServices due to complications from the use or abuse of legal and #illegalsubstances and at the same time the presence of another psychiatric
disorder. The Literature supports the hypothesis that #psychiatric disorder and substance #abuse disorder coexist more frequently than luck can
predict.
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Abstract
#Diabetes is a #metabolicdisorder characterized by abnormal
glucose uptake. It can have #deleteriouseffects on many organs of
the body, including the #oralcavity. Diabetes has an important relation
to oral health and vice versa. Diabetes increases the risk of
gum disease, #tooth decay, tooth loss, dry mouth, and various types
of oral infections. Therefore, oral and dental diseases are one of
the complications of diabetes.
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Abstract
There is lack of studies that exhaustively work on the cognitive
consequences of #psychotropicsubstance #abuse. Literature shows that the
most affected cognitive processes because this abuse is learning, memory
and cognitive flexibility. Recent data using experimental Psychology
tasks have pointed out that consumer population has significantly
greater Reaction Times than the non-consumer population in these three
cognitive areas. #Drug-rehabilitation centers must take into account
#neurocognitivestimulation within the treatments they offer to this kind
of#patients.
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Abstract
The power of addiction must never be underestimated. #Addiction is the
key element in an individual’s seeking and use of illicit drugs
despite the knowledge of the #potential #harmful consequences. The dentist
must be aware of the many oral and #dental manifestations of the use
of various drugs. Also, the dentist must be aware of the potential
systemic manifestations of drugs such as #heroin, cannabis,
#methamphetamines and cocaine in order to make the proper modifications to ensure the safe
and effective delivery of dental treatment.
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Abstract
The use of conventional #intraosseousimplants may be limited or
inapplicable in restoring some #edentulous spaces due to various
anatomical
reasons. The Cortically Fixed at Once approach (CF@O) uses the remaining
cortical #bone to fix specially designed implants. This implant system
was developed to meet challenges in patients with severely resorbed #jawbones. The CF@O protocol requires no bone graft, no sinus lift or
nerve displacements. The CF@O implant system consists of several types
of components specifically developed for different locations in the
jaw. These components are #Pterygoidimplants, compressive implants and
hybrid plates. The Pterygoid implants and the Hybrid plates are
developed to be placed in the posterior zones of the maxilla. The
compressive implants with specific macro- and micro-threads are used in
the
cortical and spongy bone, mostly in the frontal bone of the upper and
lower jaw. The hybrid #titanium plates are thin, lightweight and highly
flexible, which allows them to be adapted to any #boneanatomy and fixed
with #osteosynthesis screws.
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Abstract
#Porcelain veneers represent a reliable, predictable procedure for
conservative treatment of unaesthetic anterior teeth with an estimated
survival probability of 93.5% over 10 years. #Fracture, #chipping, color
change and #parafunctionalhabits were the most frequent complication.
This case report highlights an esthetic restoration of two discolored
maxillary incisors by tow glass #ceramiccrowns after failure related to
debonding of two porcelain laminate veneers due to pen biting.
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Abstract
Background: Central Giant Cell #Granuloma (CGCG) accounts for 1–7%
of all benign lesions of the head and neck. It often arises in the
maxilla followed by #mandible and affects children and young adults. Free
flap surgery in the #pediatricpopulation has gained widespread
acceptance regarding its technical utility and #reliability. One-stage
reconstruction combining #osseous free flaps with virtual surgical
planning
are becoming the standard for #mandibulardefects.
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Forty percent of #patients with #gastriccancer are node negative, so
they have an unnecessarily extended lymph node dissection with a higher
rate of morbidity and mortality. Successful sentinel #lymphnode (SLN)
mapping may help to reduce the number of extended #lymphadenectomy.
Sentinel lymph node biopsy (SNB) is indicated in patients with T1 or T2
tumors; primary lesions < than 4 cm in diameter; and clinical N0
gastric
cancer. The injection method and selection of tracers for SLN mapping in
gastric cancer remain controversial. However, the use of dual tracer
and in cases with non-palpable lesions, the #submucosal marking method is
recommended. The identification rate and sensitivity are the highest
in time performing SLN biopsy after dye injection ≥15 min, the number of
SLNs ≥5 and application of the basin #dissection.
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