Journals on Biomedical Science

Abstract

Several studies suggested that platelets might play a crucial role in #pathogenesis of inflammatory #boweldisease (IBD) [1,2]. There is solid evidence demonstrating that platelets, in addition to their traditional role in #hemostasis, can also function as potent #proinflammatorycells [3]. Upon activation, platelets secrete a large number of biologically active molecules able to activate an inflammatory process. At the same time, the morphology of platelets changes and their mean volume (MPV) reduces [4]. Low MPV can be a marker of activity of IBD [5]. However, the way the functional properties of  #platelets change, primarily their #aggregation capacity, remains unclear. Small platelets have lower functional abilities and larger platelets are metabolically and #enzymatically more active [6,7].

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For more Biomedical Science Articles on BJSTR

https://biomedres.us/abstracts/BJSTR.MS.ID.001041.php

https://biomedres.us/fulltexts/BJSTR.MS.ID.001041.php

Mean Platelet Volume and Aggregation in Children with #UlcerativeColitis by G Ya Levin in BJSTR