Monday, October 15, 2018

#Biocompatibility of Injectable #Microspheres by Gottfried Lemperle in BJSTR

Abstract

The increasing need for long lasting injectable #softtissue fillers for the treatment of wrinkles and skin defects, gastric reflux, urinary and fecal incontinence, and other indications requires a critical discussion of #biocompatibility based on science. Since biological fillers made of collagen will be absorbed over time, medium- and long-lasting #biomaterials have been developed in recent years. Particles of irregular shape and rough surface structure tend to initiate severe and early foreign body reactions with scattered giant cells (“#frustratedmacrophages”). On the other hand, biologically inert #microspheres with smooth surfaces are encapsulated by macrophages and fibrous tissue and will be kept in place. A review of the literature shows that most injected microspheres and particles of different chemical nature and a diameter of 20 to 65μm are #phagocytosed by macrophages. Particles smaller than 20μm are also phagocytosed but are transported by macrophages to regional lymph nodes, liver and/or lungs. Since 1 gram of medium size microspheres of 40μm has a surface area twice as large as 1 gram of microspheres of 125μm in diameter, the stimulus for associated tissue in growth is doubled. Therefore, approximately 75% of the filler volume of a medium size microsphere implant consists of the body’s own connective tissue, whereas only 40% of the filler volume #encapsulatinglargerbeads is made up of fibrous tissue.




#Biocompatibility of Injectable #Microspheres by Gottfried Lemperle in BJSTR

#Glucagonoma #NeuroendocrineTumor with the Clue of Necrolytic Migratory Erythematous Rash: A Case Report by Masoud Khoshnia in BJSTR

Abstract

Background: #Necrolyticmigratoryerythema (NME) is most commonly a #paraneoplasticcondition. It is the dermatologic manifestation classically associated with glucagonoma pancreatic #neuroendocrinetumor. #Glucagonoma syndrome has been defined by the constellation of secreting tumor associated with overproduction by the α-cells in the #pancreaticislets of Langerhans, abnormally elevated blood level of glucagon, and skin findings of NME.
Objective: Although it is not common, all physicians must have it in mind and consult for further investigation not to miss out NME.
Methods and Results: We report a case of a middle-aged female seen in clinic with longstanding skin lesions suggestive of NME revealing glucagonoma. Complete resolution of the cutaneous and systemic features occurred after surgical removal of the #tumor.




Global #Edible Vegetable #Oil Market Trends by Joe Parcell in BJSTR

Abstract

Globally, supply and demand factors have changed the #ediblevegetableoil industry. Agribusinesses have had to respond by reassessing their strategies – or their selected market positions and approach for successfully differentiating their businesses – and committing to a planning process that discovers and considers uncertainties and other factors that may change and challenge their businesses. This paper explains strategic planning in the global vegetable oil industry’s context and highlights factors that motivate U.S. and global agribusinesses to revise their #oilseed business strategic plans: customer demands, #economicconditions, policy and regulations, competitive product positioning and technical change.




Thursday, October 11, 2018

#Images Are More than Documentation: They Are Research Data by Faten Dhawi in BJSTR

 

Abstract

#Plantleaf analysis is one of the reliable methods for estimating plant’s need for #fertilization [1,2], plant pigments and physiological association [3] plant shape and pigments and genetic variation [4]. Therefore, the analysis of plant leaves is complementary part of the soil analysis #nutritional situation and shortfall in the economic #crop prevention. In order to make the best use of plant analysis, we have to pay attention to the selection of the appropriate tissue or plant organs for analysis according to plant type and age. It is worth mentioning that concentrations of different substances in plant leaves are not constant but vary according to basic conditions and #physiologicalage [5]. There are many methods for plant leaves analysis but recent trend is toward the non-destructive methods [6- 8]. For instance, leaves shape, #pigmentation and area measurements can be scored from photo. In this century, images are no longer just picture they are data [9]. There is several studies used software for images data analysis. There are Gimp [10], Image J [11] and Adobe Photoshop CS5 [12].




Advanced #Ventilator Setup by Santosh Nadig in BJSTR

Abstract

Successful mechanical ventilation requires a basic understanding of #respiratoryphysiology and #ventilator mechanics in addition to intensive nursing care. The type of breath delivered by a ventilator is determined by the combination of variables set by the #operator. This combination of settings is known as a mode. The choice of appropriate ventilator settings is largely influenced by the animal’s underlying disease process and usually requires some trial and error for each #patient. This article reviews ventilator terminology and settings, patient setup, monitoring, and some of the common complications associated with mechanical ventilation [1].




Advanced #Ventilator Setup by Santosh Nadig in BJSTR

Abdominal Dermolipectomy at #Laparotomy with Huge Ovarian #BenignTumor by Atsushi Imai in BJSTR

Abstract

Most of obese patients have more comorbidity, longer operation times, longer hospital stays, and more early and late complications. This report presents a case of severe #obesity with large amounts of redundant skin and fat extending to lower abdomen, in which a abdominal #dermolipectomy was carried out at the time of #laparotomy against giant ovarian mature #cysticteratoma.




The Polarity of Entry and Release of Canine #Coronavirus From #EpithelialCells by Annamaria Pratell in BJSTR

Abstract

#Caninecoronavirus (CCoV) is an enveloped, single-strand #RNA virus belonging to the #Alphacoronavirusgenus in the #Coronaviridae family Pratelli [1,2] Despite their labile nature, RNA viruses are able to rapidly adjust to negative pressures of immune system, generating novel strains that might have selective advantages over parental genomes. As a consequence of the high mutation frequency, in the last years CCoV has evolved and new #genotypes/ types were identified, raising several questions regarding the biology of these viruses Pratelli, Cirone and Pratelli [2, 3]. CCoVs are responsible for enteritis in dogs of all breads and ages and clinical signs may vary from mild to severe #gastroenteritis in young pups. Though fatal infections are unusual unless mixed infections with other pathogens occur or in the presence of overcrowding and unsanitary conditions Pratelli et al., [5], the virus is an important pathogen responsible for epizootics in dog population Pratelli [2]. Recently, a CCoV type 2a pantropic variant was identified in a systemic fatal disease in young dogs Buonavoglia et al., [6], and a subsequent experimental study has raised important questions on the pathobiology of CCoVs, demonstrating that the new virus was able both to infect CCoV-seropositive dogs and to induce clinical signs irrespective of the viral dose administered in the challenged dogs Decaro et al. [4].




Post Truth, Newspeak and #EpidemiologicalCausality by Jordi Vallverdú in BJSTR

Abstract

During December 2017, arose a polemic about some news which showed as Trump administration has secretly banned some words for their use in the Centers for Disease Control and #Prevention official documents, the following ones: “diversity,” “fetus,” “transgender,” “vulnerable,” “entitlement,” “science-based” and “evidence-based”. It is obvious that there are strong bonds between cultural and political agenda and scientific progress, as well as that no all researches must be automatically allowed without control. Trump is an example (but not the first one, just remind George W. Bush religious ideas that banned most of #stemcells research in the U.S.A., allowing the heading of this field to Sought Korea scientists [1], as he has already put in danger the future of several academic scientific fields [2-6]. If something has been demonstrated is that language occupies a fundamental space in Epidemiological debates: from causality to webs of causation, and, finally, to determinants [7-11]. Due to the social and complex nature of health determinants [12], it is very dangerous the political control over scientific terminology. This Orwellian scientific newspeak pushes epidemiological research to a #dangerousswamp in which only those ‘good’ concepts can be used, undermining the informational richness which allows the existence of a grounded #Epidemiology. The attack and unjustified control over scientific terms is a great mistake not only for political and democratic reasons (consider for example the recent electronic censorship war-as Julian Assange referred to- in Spain against Catalans right to decide peacefully about their future), but because is a direct attack to the heart of a ground and reliable scientific Epidemiology.




Tuesday, October 9, 2018

Characteristics of SSR Markers in #FlocculariaLuteo-virens by #RNA -Sequencing by Zhanling Xie in BJSTR

Abstract

Simple sequence repeats (SSRs) in Transcript and Unigene of #FlocculariaLuteo-virens were determined by #RNA sequencing. There were 4, 715 SSRs in 38, 988 Transcript sequences and 2, 910 SSRs in 22, 122 Unigene sequences using de novo sequencing, respectively. Mononucleotides showed the highest frequency of 26.16% in Transcript, and the ratio of #mononucleotides was A>T>G>C; while in Unigene, #dinucleotides showed the highest of 59.27%, and the ratio of dinucleotides was TG/GT>AC/CA>AT/TA>AG/GA. The SSR with 10 repeats was the most abundant in #Transcript (26.36%), while that with six repeats was the most abundant in Unigene (22.71%). Motif A had the highest frequency of 17.50% and 11.65% in Transcript and Unigene, while Motif C had the lowest frequency of l 1.10% and 1.08% in Transcript and Unigene, respectively. For the PCR products, seven primers were screened and tested from the motifs, the result were in consistent with RNA sequencing results.




Early Mobility Following Hip Fracture Surgery with Furlong Bipolar #Hemiarthroplasty-Cemented Versus #Hydroxyapatite Coated Uncemented Prostheses by Shah Jehan in BJSTR

Abstract

Mobility is an important factor in the rehabilitation phase for #hipfracture patients. Among many factors affecting postoperative mobility, stability of the stem following #hemiarthroplasty is considered crucial for early mobility. The purpose of this study was to compare early postoperative mobility in patients with cemented and uncemented hydroxyapatite coated Furlong hemiarthroplasty. We performed a retrospective comparative study to compared two groups of patients who had either cemented, or #hydroxyapatite (HA) coated uncemented implants over a period of six months. The groups were matched for their age, sex, pre-fracture mobility and accommodation prior to injury. Their early post-operative (day1-day7) mobility was assessed based on their walking distance, need for support, and pain level. The length of hospital stay and discharge destinations were also recorded and compared between the groups. Each group had 22 patients. The average age was 84 years (range, 74-95). The average pre-fracture mobility score was 5.5. The average post-operative mobility for cemented group was 2.7 at day 1 and 6.3 at day 7. For the uncemented group the average post-operative mobility at day 1 was 3.7, and at day 7 it was 6.9. Hospital stay was slightly longer in the cemented group. We conclude that early post-operative mobility is slightly better in patients who had HA coated uncemented implants. The average hospital stay is longer in the group with cemented implants.




#Brain MR #Diffusion Tensor Imaging for Multi-Site Studies: A Review by Youngseob Seo in BJSTR

Abstract

This article provides a review of quality assurance and control issues in multi-site #diffusiontensorimaging (DTI) studies for the evaluation of #microstructuraldamage to white matter structures. In order to perform comparatively quantitative analysis of tensor metrics, tensor data must be of high quality and reproducible which requires documentation of scanner #stability, minimization of artifacts, and optimization and standardization of image parameters. I review various practical aspects of DTI which impact quality of DTI with the focus on the quantification of tensor metrics.




Inadequate Nitrogen #Fertilization: Main Cause of the Low Seed Yield on the Chia Crop (#Salvia hispanica L.) by Anacleto Sosa Baldivia in BJSTR

Abstract

Chia (#Salvia hispanica L.) is a Mexican ancestral crop that for its nutritional properties presents high demand in the international market, its growth rate is 239% annually and it is estimated that by 2020 its sales will be $ 1.2 billion dollars [1]. Since 1917, it has been reported that the maximum attainable seed yield (SY) on chia is close to 3.0 t ha-1 [2-5]; however, the SY that the farmers commonly achieve in commercial plots is lower, and on average it only is 0.36 t ha-1 [6]. According to [7], the low productivity on chia due to their #agronomic management has not been modernized, and to this date it still is cultivated mainly on rainy season, and the use of #fertilizers, pesticides and improved varieties is scarce. The plasticity of the chia to adapt and produce under a low-input systems has led erroneously to assume that it presents low requirements of water and fertilizer [8,9], and also it resists the attack of pests and diseases [10].




#Amphetamine Use Induced Takotsubo Cardiomyopathy Treated With #Venoarterial Extracorporeal Membrane Oxygenation by Kamler M in BJSTR

Abstract

#Extracorporeal life support (ECLS) is a powerful tool for cardio respiratory support in #cardiogenicshock. A 24 year old female patient was admitted with acute #heartfailure due to #amphetamine use and emotional stress leading to #cardiacarrest. After successful treatment with ECLS the patient was discharged from hospital at day 14.




“Is Continuous Passive Motion Beneficial for Early #PostOperativePeriod in TKA Patients?” by Syed Kamran Ali Shah in BJSTR

Abstract

Objective: To evaluate the effectiveness of Continuous Passive Motion in adjunctive with conventional physical therapy in early post operative Total #Knee #Arthroplastypatients.
Methods: Total 150 patients were enrolled, randomly selected in two groups, CPM (n=73) and Control group (n=75), as 2 patients from CPM group refuse to participate in study. In control group patients received conventional #physicaltherapy intervention alone, while in CPM group patients received conventional physical therapy intervention along with CPM application. Assessment of all patients were carried out twice by experience #physicaltherapist, once at the preoperative visit 2 weeks prior to TKA for baseline measurements and second at discharge after 7 days post operatively. Outcome assessed among both group by assessing active knee range of motion primarily #flexion and extension by using Goniometry and as secondarily outcome pain, stiffness and functional difficulty by using WOMAC questionnaire score.




#Dental #Fluorosis- Revisited by Abhimanyu Mohanta in BJSTR

Abstract

#Dentalfluorosis is a chronic #fluoride–induced condition in which an excess of fluoride is incorporated in the developing tooth enamel and disrupt the enamel formation of the tooth. Prevalence of dental fluorosis due to high levels of fluoride in drinking water is an endemic global problem. Although, definite mechanism of dental flourosis is yet to be confirmed, #hypomineralization of #teethenamel is the real fact and so the teeth enamel become more porous and softer than the normal counterparts. More exposure to the fluoride, greater is the rate of dental fluorosis. Also, children with mild dental fluorosis had lower IQ than those without dental #fluorosis demands further investigation.




#Dental #Fluorosis- Revisited by Abhimanyu Mohanta in BJSTR

The Concepts of “#PatientSuffering” and “#FavorableInteraction” in Nurse-Patient Conflicts Based on Gaps in Perception by Mayumi Uno in BJSTR

Abstract

Aims and Objective: To determine nurses’ and #patients’ perceptions regarding nurse-patient conflicts.
Background: Nurse-patient conflicts, and both parties’ responses to them, are known to influence patients’ perceptions of the quality of nursing care. However, there remains a need to better understand and conceptually interpret both parties’ perceptions, which this study aimed to fulfill.
Design: A qualitative study aiming to create a conceptual model.
Method: #Participants were nurses attending nurse-manager training courses and phone #counselors who handled calls from patients seeking advice. Descriptive surveys were distributed to 320 nurses in August and November 2012, January 2013, and June 2014. We further conducted 8 interviews with phone counselors in December 2013 and January-February 2014, which were also supplemented with existing data from a previous study.




#OvalCells: Potential Role in #LiverRegeneration by Hussein Abdellatif in BJSTR

Abstract

The #liver has the specific capacity to regulate its growth and repair. The healing process in the liver is characterized by the #proliferation of all existing cell lines within the liver, including hepatocytes, #epithelialcells that line the #canaliculi, endothelial cells, and Kupffer and HSCs cells. The liver also contains “stem” cells or liver progenitor cells (oval cells in rodents) that can be activated by liver damage. #Ovalcells are the progeny of stem cells. They can divide rapidly but in contrast to stem cells do not possess the ability to self-renew. Oval cells have the potential to generate more than one differentiated cell type but cannot be serially transplanted. During liver regeneration, oval cells are essential at forming a second line of defense. In this article, we review some aspects of oval cells, characters, role in normal regenerative process as well as its role in liver diseases and #malignancy besides its potential applications as source of cellular therapy.




Effect of Additional Instrumentation with the Xp-Endo Finisher versus the #SelfAdjusting File on the Push-Out #BondStrength of Different Sealers by Emre Bayram in BJSTR

Abstract

Objectives: To compare the push-out #bondstrength of root fillings made with either 2Seal or TotalFill BC sealer after the additional instrumentation of oval canals with either the XP-endo Finisher (XP) or Self Adjusting File (SAF) systems.
Material and Methods: #Mandibularpremolars with single oval canal were collected for the study. #Rootcanals were prepared with Reciproc R25 and were randomly divided into six groups (n=10), as follows: group 1, additional instrumentation with SAF and filling using 2Seal and gutta-percha (GP); group 2, additional instrumentation with SAF and filling using Total Fill BC and GP; group 3, additional instrumentation with XP and filling using 2Seal and gutta-percha; group 4, additional instrumentation with XP and filling using Total Fill BC and GP; group 5, #canalfilling with 2seal and GP without additional instrumentation; group 6, canal filling with Total Fill BC and GP without additional instrumentation. Each sample was sectioned horizontally into 1 mm thick slices at each thirds and push-out test was performed using universal testing machine. Three-way ANOVA and Tukey’s post-hoc tests were performed to compare groups.




Monday, October 8, 2018

Management of Complicated Crown-Root #Fracture Using Newer Radiographic #AIDS - A Case Report by Dolly Rathod in BJSTR

Abstract

#Crownroot #fractures are complex traumatic injuries that require multidisciplinary management and may afford uncertain prognosis. Diagnosis of such cases is often difficult. With the newer #radiographicaids like CBCT, the diagnosis is more definite and hence treatment outcome can be more predictable. This case report discusses the use of newer radiographic aids and treatment options for fractured teeth with the concept of intentional re plantation as an option to manage complicated crown-root fractures in permanent #anteriorteeth.




#Sterilization Validation of #Pharmaceuticals by Shaziya Yasmeen Sayeed in BJSTR

Abstract

Bioburden is measure of microbial contamination or #microbialload; the amount of #microorganisms contaminating an object. Each lot of a component, drug product container, or closure with potential for #microbiologicalcontamination that is frightful in perspective of its planned utilize might be subjected to microbiological tests before utilize. Appropriate written procedures, designed to prevent objectionable microorganisms in drug products not required to be sterile, shall be established and followed. Microbiological monitoring of the manufacturing environment can serve as an adjunct to control and generally is a qualitative assessment tool in a properly implemented formal risk-based microbiological control program. A monitoring program corresponding with the product bioburden risk can help confirm the effectiveness of microbiological controls and may facilitate early detection of potential problems. The techniques utilized for microbial monitoring should be capable of isolating the numbers and types of organisms that have been deemed significant relative to in-process system control and product impact for each individual system.




#Biocompatibility of Injectable #Microspheres by Gottfried Lemperle in BJSTR

Abstract The increasing need for long lasting injectable #softtissue fillers for the treatment of wrinkles and skin defects, ga...