Thursday, July 18, 2019

Immunological Diseases - BJSTR Journal

Abstract

A few years ago, a colleague of mine wrote an opinion piece on the fact he believed we are not developing specialists in exercise science, only generalists. Therefore, a decline in the advancement of the field has begun signaling a less than productive period for the area of study. For a while now, I have pondered this point of view and I cannot disagree with it on one level. Having our undergraduate and graduate students dive as deep into the cardiovascular physiology or #biomechanics as they can is a wonderful opportunity for those students (and faculty) to grow intellectually and hopefully expand the current body of knowledge as some like to say. On the other hand, an absolute pioneer and leader of the vanguard currently sweeping #human fitness performance has said that exercise science has no tangible place in the application of training and athlete development. At first, I was offended by this notion. What is he talking about? I have been in the #exercise science in one form or fashion for almost thirty years and find the information I have acquired extremely useful in athlete development, coach development and student development. Just as I had done with my colleague's words, I suppressed my ego and let things percolate. My opinion that eventually developed was of agreement. He was correct. The current structure of most exercise science programs does not look to guide the student's in the development of applicable skills to move human performance forward. We are specializing in not specializing and that is causing a stagnation in a form of isolation. We have limited ourselves. Limited to exercise physiology, biomechanics, #kinesiology and other specialized classes that, more often than not, are silos - boxes to be checked for a student to qualify for graduation. We are not developing students that see the human machine as it is, integrated.

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Neurological Disorders - BJSTR Journal

Abstract

#Medical databases are fundamental for developing new techniques for early detection of #neoplastic cells. They are however difficult to obtain, since the labelling of the images is often operator dependent, requires specialized skills and the written informed consent of the patient. The variability of structures in biological tissue poses a challenge to both manual and automated analysis of histopathology slides. Although some authors showed moderate to good agreement among expert pathologists, and satisfactory results on their #intra-observer reliability, other studies found that even experienced pathologists frequently disagree on tissue classification, which may lead to the conclusion that solely using expert scoring as gold standard for #histopathological assessment could be insufficient. Hence, there is a growing demand for robust computational methods in order to increase reproducibility of diagnoses. In this note we present a database containing images of preneoplastic and neoplastic colorectal tissues and in a forthcoming paper we will describe our proposed DL algorithm to classify them into the following categories: normal mucosa, early #preneoplastic lesions, adenomas, cancer. #Colorectal cancer ranks among the three most common cancers in terms of both cancer incidence and cancer-related deaths in Western industrialized countries [1]. Every year in the world nearly 1.3 million new cases of CRC are reported and nearly 700.000 patients die [2]. Lifetime risk of colorectal cancer may reach 6% of the population living in developed countries. CRC is second in incidence in Europe only to lung cancer, and it causes around 204.000 deaths every year [3].

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Preventive Medicine - BJSTR Journal

Abstract

Our patient presented with symptoms resembling acute appendicitis, during #diagnostic laprascopy a #retroperitoneal hematoma without palpable Aneurysm was found, because the patient was hemodynamically stable. It was decided to carry out further #radiological investigations, a computed tomography revealed a right sided solitary iliac artery aneurysm and a retroperitoneal hematoma and because we were sure about the diagnosis endovascular reconstruction was done, patient recovered nicely, and the retroperitoneal hematoma was reabsorbed spontaneously, and patient was Send home after 7 days. 40 years male patient was presented to the emergency department complaining from pain at the #right iliac fossa area for the last 48 hours. On clinical examination there was right lower quadrant peritonitis with no palpable mass, body temperature was 37.8 c and the patient #leukocytosis was 18000, ultrasound was done, and it was not conclusive because of dilated loops of bowel, rebound tenderness was positive, psoas sign was positive. Acute appendicitis was suspected, and laparoscopic appendectomy was planned to be done under general anesthesia. The view was poor and a decision of laparotomy to be done is taken at the same session. There was a normal appendix and a retroperitoneal hematoma on the lateral side of the cecum. The retroperitoneal hematoma was pulsating, and it was a very clear vascular problem, since the patient was hemodynamically stable the operation was terminated with the diagnosis of retroperitoneal hematoma which needs further investigations postoperative CT scan (Figures 1-3) showed a right iliac artery aneurysm with the diameter or 4cm and a retroperitoneal #hematoma. As with aortic aneurysms size seems to be the most important determinant.

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Wednesday, July 17, 2019

Journals on Regenerative Diseases - BJSTR Journal



Abstract

Introduction: In the present era, cigarette smoking is a major but preventable cause of death. Despite being aware of its harmful and hazardous effects, many young adults begin experimenting with cigarettes at a very early age and then adopt it as a regular habit.
Objectives of the Study: The basic objective of our study is to analyze the effects of smoking on lung function, and respiratory muscle strength of Pakistani youth.
Methodology of the Study: This study was conducted at Services institute of medical sciences, Lahore during 2017. Youth male subjects aged 12 to 18 years participated in this cross-sectional study. #Socio-demographic values and medical history of the selected patients were recorded clearly. Prior to participation in this study, each subject signed an informed consent form to comply with the ethical guidelines.
Results: Most subjects started cigarette smoking between the ages of 15 to 18 years. The most common duration of cigarette smoking was 1-3 years. Three major parameters, chest expansion, lung function using #spirometry, and respiratory muscle strength, were compared and these all are high in smokers.

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Journals on Vaccination - BJSTR Journal

The #adolescent students are faced with a numbers of challenges at home, school and other social cultural environment. In contemporary times little emphasis have been drawn by researchers, the academicians and scholars on challenges facing the adolescent students taking into consideration culture shock. This is due to the fact that as an adolescent move from one cultural environment to another, either one home to another or school to another, he/she often experience challenges/problem of adjusting culturally to suit the expectations of the new culture. This tends to have interplay in their academics, social, emotional, psychological, and #behavioural life. It is in consonance with this fact that this paper deems it fit to investigate the effect of culture shock on the adolescent student and proffer necessary solution insight in terms of remedies. The concept of culture shock and adolescent students as used in the study were explained. Effects of cultural shock on the adolescent students were communication defectiveness, academic retardation, conflict, emotional imbalance, deviance, aloofness and withdrawal from peers; strategies identified to remedy culture shock were counseling, awareness campaign, acculturation, and co-operation. Based on the findings of the study it was recommended that there should be #keen collaboration between the government, parents, school authorities and non-governmental agencies, which will help in mapping out strategies that will assist the adolescent to cope with cultural shock and make meaningful contribution financially to carry out such mandate.

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Journals on Psychology - BJSTR Journal

Abstract

With the development of surgical methods and #pharmaceutical preparations, more patients with benign #end-stage lung disease can receive treatment of lung transplants. Not only the number of surgeries has increased to 4,000 per year, but also the survival time has been growing longer. Ten years ago, a lot of medical experts thought that #post-transplant lymphoproliferative disease was a rare disease, but this disease has received more and more attention because of increasing of surgeries. PTLD is a serious and rare post-transplant complication. Compared with other organ transplants, the incidence of heart, lung, and heart lung transplantation is extremely high. The 5-year survival rate is 29%, and the median survival period is 10month. Risk factors for morbidity are related to the use of #immunosuppressive agents, viral infections, type of transplanted organ, gender, age et al. This article will describe the incidence, risk factors, pathogenic mechanism, treatment methods and latest research progress of #lymphoproliferative diseases after lung transplantation recently by providing new ideas on hotspots. Lung transplantation is the only effective way to treat benign lung disease of end-stage. Vladimir performed lung transplant surgery on animals for the first time 70 years ago epically [1]. Soon after, Hardy did the first human lung transplantation 12 years later [2]. But patient only lived 42 days after the transplant by limiting to the development of surgical techniques and drugs. The emergence of immunosuppressants represented by #cyclosporine (CsA) in 1983 significantly pulled the survival rate after lung transplantation to a new level. Afterwards, the median survival time after transplantation can reach 5.3 years [3].

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Tuesday, July 16, 2019

Regenarative Medicine - BJSTR Journal

Abstract

Statistics describes insufficient effectiveness of traditional methods of therapy in patients with #neurodestructive processes. Implementation of cell technologies in traumas and brain attacks increases effectiveness of recovery processes when standard therapy is combined with stem cells (SC) implantation. What is the reason for such positive demonstration of brain plasticity and activation of reparative processes? There are different opinions on that scope [1-4]. The answer is important for viability of cell technologies in recovery of neural network structures in #brain trauma. Local trauma in sensorimotor area of cerebral cortex was simulated in rats weighing 230g (n=9) in stereotaxic apparatus after #ketamine-xylazine-acepromazine anesthesia (55.6, 5.5 and 1.1, mg/kg, i/p, respectively). Culture of mesenchymal stem cells (MSC, 30000 per 1ml) was implanted into submucosa of nasal cavity in the amount of 100|il of culture medium. MSC were previously marked with FITC-labeled PH678. Slices 8|im in thickness were prepared in one week after decapitation, MSC distribution was visualized using Zeiss AxioVert 200M fluorescence microscope with Zeiss AxioCam HRm CCD camera. Dissociated culture of neuron-like cells of rat pups' (n=15) cerebral cortex was in vitro cultivated on glass matrix for one week. Surface of matrix was treated with #polymer (3,4 ethylenedioxythiophene). These in vitro experiments are necessary for analysis of transformation dynamics of dissociated neuron-like cells to neural network. Figure 1 shows diffuse distribution of fluorescent formations in sensorimotor brain area. The picture is associated with the Milky Way at night. So, Figure 1 demonstrates vast distribution of perineurally implanted MSC in the area of local brain trauma.

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Journals on Regenerative Diseases - BJSTR Journal

Abstract

Roughly 22% of all pregnancies end in an abortion [1]. This rate goes up to as much as 75% in pregnancies occurring in advanced age. Normally once women seek counselling with bleeding in early pregnancy mostly the standard method of finding viability has been clinical evaluation, doing an #ultrasonography along with quantitative #HCG levels and repeated USG for confirmation of a missed abortion causing loss of time and emotional sequelae [2]. Robinson et al. [2] quoted that stress and #anxiety is worst at the time of initial knowledge than the depression that follows the final miscarriage [2]. Garcia [3] reviewed the risk factors for these. Importance of making an early diagnosis is that one can stop the medications like P or oral anticoagulants, while those who have an ongoing IUP, one can reassure the patient and observe her medically. Recently based on the physiological knowledge that alpha protein (AFP) is produced by yolk sac and later on by the fetal liver [4], as early as the 5th week of #gestation, AFP can be measured from the #embryonic tissue. In fetal serum AFP is>=1000 times higher than the maternal serum [5]. Thus Mor [6] hypothesized if AFP concentration in vaginal blood which contains dissolved fetus tissue is higher than #AFP concentrations in maternal serum. Thus, they tried to find if relatively high AFP concentrations in early 1st trimester or early second trimester vaginal blood will confirm the presence of an IUP which has failed i.e. a missed abortion or incomplete abortion since it contains dissolved fetal tissues [6].

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Scientific Research Articles on Biomedical - BJSTR Journal

Abstract

Introduction: Mosquitoes are slender, flying insects of the order diptera (true flies) in the arthropod Super-Phylum. They are deadly insects transmitting diseases such as malaria, elephantiasis and several #arboviruses. The adaptability of mosquitoes is a problem and this is tantamount to greater spread of diseases. Malaria is the most widespread mosquito borne disease in Nigeria where it is holoendemic.
Aim: The source of malaria problem is the diverse breeding sites of mosquitoes. This work investigates preferred mosquito breeding water sites, #physicochemical factors and colour cues influencing oviposition and development of mosquitoes.
Methods: Investigations were carried out on the preferred oviposition and breeding water sites of mosquitoes in the wild during the rainy season. 100 CL of water were collected from five water samples each of packaged water, polluted water, pond water, tap water and rain water. The water samples were transferred to five green and five transparent containers (200CL) each and left opened in a well ventilated laboratory overnight for four weeks. Daily temperature and weekly Hydrogen ion concentration (ph) of the water in each container were taken.
Results: It was observed that mosquitoes oviposited in the ten containers continuously. The two mosquito genera identified were Anopheles and Culex specie using their developmental stages as #morphotaxonomic indices. More Anopheles spp (57.2%) oviposited than Culex spp (42.7%) although this was not statistically significant. The polluted water had more Culex specie while the rain water had more Anopheles species with no regard for the colour of the container. Green colour did not serve as a significant cue for oviposition. Packaged water had the least mosquitoes of both species. There were no significant differences in temperature and Ph ranges of all sampled water in both containers.
Conclusion: Mosquito breeding occur right in homes as humans indulge in #malariogenic lifestyles. Objects, excavations, plants and anything that can hold water must be eliminated. Water storage containers should always be covered. This work suggests control programmes must put into place preferred breeding sites of mosquitoes. Enforcement of environmental sanitation by cleaning drainages and open gutters around homes will go a long way. Education of the populace on mosquito breeding sites in homes is advocated.

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Monday, July 15, 2019

Journals on Medical Casereports - BJSTR Journal



Abstract

In chronic experiments on rabbits, we demonstrated that electrolytic destruction of the dorsal #amigdalofugal way - stria terminalis results in intense depression of the integral electrical activity of the hippocampus. Morphological changes in neurons and satellite glial cells, such as lysis of the Nissl substance, hyperchromatosis, and wrinkling of the cells after destruction of the #stria terminalis, were proof of the correctness of our conclusion. It is postulated that one of the main factors underlying the generalized effects observed in our experiments is probably the disturbance of functional characteristics of the #hypothalamo- hypophyseal neurosecretory system induced by destruction of the #amygdalofugal connections; this disturbance results in significant pathological shifts of metabolism in the hippocampus. The study of the hippocampal theta rhythm is one of the urgent problems of modern neurophysiology. The medial septum nucleus, standing at the entrance to the hippocampus, demonstrates the importance of this education [1,2]. In addition to the data indicative of the pacemaker role of the septum, there are works which demonstrated the a definite role of stem-diencephalic structures in mechanisms of formation of hippocampal theta rhythm: of great importance given to the reticular formation [3], the hypothalamus [4], the thalamus [5], locus cereleus [6], nucleus raphe [7], etc. In order to study the role of amygdalo- hypothalamic connections in the processes of formation of the hippocampal theta rhythm in this study was conducted electrical stimulation and destruction of the dorsal (DAP) and ventral amygdalofugal pathways (VAP). After #electrophysiological studies was conducted a morphological analysis in neurons and glial cells in various areas of the hippocampus and the medial nucleus of the septum.

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Journals on Medical Microbiology - BJSTR Journal

Abstract

Background: #Sigmoid diverticulitis is a common #abdominal disease that may require emergency treatment. The prognosis depends on the potentially dangerous complications, in particular #pylephlebitis and #hepatic abscess.
Case Report: We report the case of a patient with sigmoid diverticulitis, due to the ingestion of a foreign body, impacted in a diverticulum, complicated by pylephlebitis and hepatic abscess. The patient was treated by endoscopic extraction of the foreign body, antibiotic therapy and #anticoagulation. Evolution was favorable. Sigmoid diverticulitis is one of the most common abdominal diseases requiring emergency treatment in Western countries. Conservative medical treatment often leads to the regression of symptoms, but some complications can be life threatening. Septic dissemination by contiguity (peri-intestinal abscesses/ generalized peritonitis) or hematogenous (pylephlebitis/hepatic abscess) may occur [1]. The suspicion of complications is based on clinical signs and symptoms (#hyperthermia, abdominal pain, sometimes the presence of a palpable abdominal mass), and on blood tests showing an inflammatory response. However, the gold standard for the diagnosis is abdomino-pelvic computed tomography (CT) with injection of an iodinated contrast agent. A CT-scan is superior to ultrasound and magnetic resonance imagery for the visualization of deep #intra-abdominal abscesses and #septic thromboses due to its better spatial resolution and its greater acquisition range [2].

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Journals on Neuro Imaging - BJSTR Journal

Abstract

Background: The effect of #chronic kidney disease (CKD) on the long-term prognosis of patients with #atrial fibrillation (AF) undergoing coronary stenting was less studied.
Methods: We enrolled 2,511 patients with nonvalvular AF undergoing coronary stenting between January 2010 and June 2015 from 12 hospitals in Beijing, China.
Results: 22.9% had CKD (creatinine clearance <60ml/min). Compared to those with preserved renal function, patients with CKD were older, and had the higher prevalence of women, hypertension, previous ischemic stroke, cardiac dysfunction, and anemia. All patients were treated with drug-eluting stents. Dual #antiplatelet therapy was the dominant #antithrombotic strategy in both groups (96.0% vs. 93.9%, P=0.054). The follow-up duration was 39.5±18.6 months. Complete follow-up data was obtained for 95.3% of this cohort. CKD group had higher incidences of death (19.0% vs. 6.9%, P<0.001), ischemic stroke (5.5% vs. 3.3%, P=0.020), MACCE (a composite of all-cause death, non-fatal myocardial infarction, target vessel revascularization, ischemic stroke and arterial #thromboembolism, 28.2% vs. 14.7%, P<0.001) and Bleeding Academic Research Consortium (BARC) ≥ grade 3 (2.4% vs. 0.8%, P=0.003). No significant difference was noted with regard to myocardial infarction and target vessel revascularization. Cox multivariate regression identified CKD as an independent risk factor for all-cause death (Hazard ratio [HR]: 1.85, 95%CI: 1.37-2.50), MACCE (HR: 1.56, 95%CI: 1.25-1.96) and BARC ≥3 bleeding (HR: 3.14, 95%CI: 1.49-6.61), but not for ischemic stroke (HR: 1.10, 95%CI: 0.67-1.79).
Conclusion: CKD was independently associated with poor long-term #prognosis except for ischemic stroke in patients with AF and coronary stenting.

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Sunday, July 14, 2019

Journals on Regenerative Diseases - BJSTR Journal



Abstract

#Ileocecal intussusceptions represent a not rare cause of colic in horses; different technique is described to surgically treat this lesion and the report point its attention to the #partial ileal bypass focusing on the long term follow-up and possible complications of this procedure. Six horses presented for signs of abdominal pain underwent a clinical, #ultrasonographic and #rectal examination where a presumptive diagnosis of ileocecal intussusception was made in all but one patient. All horses underwent exploratory laparotomy where a definitive diagnosis of ileocecal intussusception was made; #a jejuno-cecostomy with no resection of the ileum (partial ileal bypass) and no reduction of the lesion was performed in all the patients. The follow up revealed no long-term complications in all the horses. Colic can be considered as one of the leading causes of death in horses, and although the majority of cases can be managed with a medical approach, a small percentage requires surgery to avoid a fatal outcome [1]. Several studies in recent decades have investigated the survival rates and complications after colic surgery, focusing attention on the variables that may affect the outcome [2- 4]. According to one study [2], surgical lesions affecting the ileum, or the ileocecal junction were found in 6.6% of a group of 300 horses; ileocecal intussusception occurred in 1.3% of the entire sample. This lesion often occurs in young horses, and the initial clinical signs vary from an acute colic syndrome to chronic weight loss and poor body condition. Ileocecal intussusceptions are not always easy to diagnose on clinical examination because of the position of this organ in the abdomen. Surgical treatment of this part of the small intestine can be challenging because of the inability to exteriorize the most caudal part of the ileum, close to the ileocecal junction. Different surgical approaches can be considered for the treatment of ileocecal intussusceptions. English language literature includes studies describing manual reduction of the lesion or resection of the involved segments and a subsequent complete bypass of the ileum, jejunocecostomy with transection of the ileum [2,5,6].

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Biomedical Research Articles - BJSTR Journal

Abstract

This article provides a summary of the history and actual state of #agricultural science and production (including land reclamation, soil erosion and #salinization, and much more, study that is one of the main types of scientific activity of the Institute erosion and irrigation of the Azerbaijan National Academy of Sciences) in Azerbaijan. Figure 1 Irrigated agriculture problems in Azerbaijan, it should be noted that due to the complexity of the physical-geographical conditions and 41.8 per cent of #anthropogenic impact in one way or another affected by erosional processes. Currently land in Kurlowland delimited by the heavily polluted [1]. The total number of saline lands in the Republic is about 1000 thousand hectares, although some of them are equipped with collector-drainage network. For their washing and recovery requires additional fresh water. Traditionally, water-intensive crops are grown in Azerbaijan. And water consumption per hectare of irrigated land behind the water shortage, leaving instead of 6-7 irrigation plants receive irrigation 2. As is known, Azerbaijan differs from all other regions in climatic conditions of 11 climatic zones existing in nature, 9 happens in our Republic [2]. This fact requires a special approach to solving the problems of #agricultural production. The situation is further complicated by the fact that rainfall in the Republic is very uneven, and in some regions is not enough to meet the needs of crops during their growing season. the presence of water shortage. Water resources of Azerbaijan make up 32.3 billion cubic metres per year, and in dry years this figure is reduced to 23.16 billion cubic meters (95% off). Of these water volumes their own water resources are 10 billion m3 .

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Journals on Biomedical Imaging - BJSTR Journal

Abstract

#Pelvic floor dysfunction is a complex of disorders of the #fascialstructures and pelvic floor muscles that keep the pelvic organs in a normal position and provide continence of urine and feces [1-6]. The POP amounts 30.8% in the structure of urogynecological pathology in European countries [7], in the Middle East countries - 19.9-49.6% [4], in the countries of North and East Africa - 46-56% [8]. In recent years, the incidence of POP has been increasing worldwide [9]. However, despite the growing prevalence of pelvic floor dysfunction in women, there is no consensus on its etiology and #pathogenesis to date. Herewith, there is no doubt that this is a multifactorial pathology, the development of which is determined by genetic and environmental factors. The environmental factors contributing to the development of pelvic floor dysfunction in women have been studied quite well. Those include traumatic and prolonged labor, estrogen deficient conditions, diseases accompanied with increased #intra-abdominal pressure (bronchitis, bronchial asthma, constipation, etc.), disturbance of #microcirculation of blood and lymph in the small pelvis, obesity, and sedentary lifestyle [5,10,11]. As for genetic factors, already at the beginning of the 20th century it was known about existence of family cases of POP. This fact served as the basis for conducting large-scale studies using classical methods of genetic analysis – clinical-genealogical, population-statistical and twin studies, aimed to elucidate the role of hereditary factors in the development of pelvic floor dysfunction in women. The generalized results of these studies have convincingly demonstrated that in families of probands (patients) a pelvic floor dysfunction occurs 3-5 times more often than it would be expected based on the frequency of this pathology in population.

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Friday, July 12, 2019

Journals on Biomedical Intervention - BJSTR Journal

Abstract

Introduction : Consequently low back pain to the government and other employers (#Healthcare industry) include high cost of workers’ compensation insurance to be paid to injured workers, recruitment or training costs and lost time This study sought to address the objectives : To determine if there is significant relationship between people suffering from low back pain and work related #absenteeism and to determine if there is significant relationship between people suffering from low back pain and social disruptions.
Design: This was a qualitative and quantitative using questionnaire, interviews and focus groups discussion.
Setting and Participant: This study comprises of all healthcare workers present in Kibuli Muslim Hospital, Kibuli-Uganda
Methods: A cross-sectional survey was employed and a total number of 150 self-structured questionnaires were distributed among healthcare workers and this was used to determine the prevalence of low back pain and work-related absenteeism. Data was entered using Epi info soft-ware and analyzed using SPSS
Results: The study highlighted the #debilitative effects of low back pain among the healthcare workers has affected their loss of working days and social disruptions (experiences of isolation, inability to pursue hobbies and leisure activities).
Conclusion: The findings from this study revealed the outcome that should be measured in studies that will be evaluating the treatment of excruciating effects low back pain among the healthcare workers and also a better understanding of appropriate #intervention.

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Journal on Medical Genetics - BJSTR Journal

Abstract


#Pediatric palliative care is still a young, but rapidly growing field world wide. There have been a number of children’s hospitals creating palliative care services over the past two decades. Both the American Academy of Pediatrics and Institute of Medicine have focused attention on increasing the care access for children with life-threatening or life-limiting medical conditions. Data has shown the beneficial effects of inpatient palliative care services, not only on assisting control of #physical symptoms like pain but also to ameliorate the suffering and maintain dignity that is appropriate for the culture, religion and upbringing of the family. The service has shown to improve patient satisfaction and decrease the length of stay. Various studies have projected newly formed pediatric palliative care teams initial struggles, periods of quiescence with variable levels of growth and success over subsequent years. All primary and repeat referrals to pediatric palliative care were recorded over the first year after the service was created. Direct interventions with staff included division meetings with #pediatricpulmonology, NICU and PICU to discuss the role of palliative care. Huddles were done with the nursing staff from NICU, PICU, Pediatric Oncology and the Pediatric floor and meetings were conducted with the social workers covering these units. Other interventions included grand rounds, website creation, and lectures on palliative care to medical students.

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Journals on Medical Casereports - BJSTR Journal

Abstract

The aim of this study was to compare the conventional healing screw with custom healing screw in terms of maintenance of soft tissue architecture. Twenty-four patients who underwent single tooth extraction and single immediate implant placement were included in the study. Twelve patients were treated with conventional healing screw after immediate implant placement (control group) and 12 were treated with #screwretainedcustom healing screw (test group). After minimally traumatic tooth extraction, a temporary abutment was fabricated utilizing #flowablecomposite, which adapted to the socket architecture, to serve as a customized healing screw. In order to evaluate soft tissue remodeling in all cases, digital impressions were made before tooth extraction, at implant insertion, at 6 months after insertion, and after placement of the final restorations. After 6 months of the #Osseo integrated period, the custom healing screw served successfully as a tooth profile for peri-implant tissue. In cases of implants with conventional healing screw, soft tissue remodeling around the implants is observed, in contrast to cases of custom healing abutments. Correct design of a healing abutment is important for maintaining the emergence contour in cases of immediate implant placement. In our study, a considerable difference was observed between the standard #healing screw and customized healing screw. The selection between provisional restoration and customized healing abutment is only based on #esthetic considerations.

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Thursday, July 11, 2019

Journals on Biomedical Intervention - BJSTR Journal

Abstract

The study of prevalence of malocclusion is one of the common problem of #orthodontics. Study of the epidemiological data on the prevalence of malocclusion is an important determinant in planning appropriate levels of orthodontic services. The occurrence of occlusal anomalies varies between different countries, ethnic and age groups. Also, #malocclusions have a #multifactorial origin and can hardly ever be attributed to a single specific cause. Causes include general factors, such as genetic and hereditary components, nutritional deficiencies and abnormal pressure habits or local factors located directly in the dental arch such as supernumerary teeth, tooth decay and premature loss of primary teeth. In patients with occlusion anomalies is important aesthetic complaints, which causes to inferiority complex. Analysis of Literature data confirms dental anomalies frequency around the world. Its frequency varies from 11% to 70%. The objective of this study was to determine the prevalence of malocclusion among school children of Georgia. The sample consisted of 500 children (316 females, 184 males) in the age group of 6-15 years. Epidemiological data, the malocclusion has the third highest prevalence among #oral pathologies, second only to caries and periodontal disease. It is therefore in the third position of the scale of priorities as to the dental problems of Global Public Health, according to WHO [1]. Age is the main determinant for progress of any disease. In context to the specialty of Pedodontics and Orthodontics, some developing malocclusions may get selfcorrected with the progress of age. It is necessary to carry out #epidemiologic studies of malocclusion in all regions at different age groups to grade the severity of malocclusion according to the respective age groups [2]. The causes that promote the evolution of this process are very diverse, which makes the malocclusion to be considered multifactorial, with #hereditary, congenital, functional, environmental influences and nutritional, socioeconomic and educational factors [3].

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Journals on Medical Informatics - BJSTR Journal

Abstract

Adult women, living in a contemporary world are exposed to a series of #illnesses. A faster and more demanding professional lifestyle creates more stressful situations. The productive age, besides general good health condition also requires the right appearance. The skin as an organ, that is the most visible reflection of our inner condition and each physiological abnormality of organism can show itself in skin changes. That is exactly what happens in case of #acne vulgaris among adult women. Everyday exposure to stress also seems to be one of the potential factors worsening the condition of skin of patients with acne. The nervous tension may cause the activation of inflammatory conditions of skin and appearance of #exanthema [1]. Patients suffering from the problem of acne display much higher mental pressure than those suffering from other chronic diseases such as diabetes or asthma. Approximately half suffer from low self-esteem, and in drastic cases, it may lead to depression or suicidal attempts [2]. Scientists who research large groups of probands agree with #Loughlin, that the illness may appear also in maturity [3]. The most characteristic skin changes for acne vulgaris are first blackheads and whiteheads, more seldom papules and pustules

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Immunological Diseases - BJSTR Journal

Abstract A few years ago, a colleague of mine wrote an opinion piece on the fact he believed we are not developing special...