Abstract
The production and accumulation of gases in the intestine has been
reported more frequently in recent times. Accumulation of gas in
the intestine without proper remediation has been associated with
several pathologic morbidities and consequently mortality in unattended
cases. Intestinal gases are primarily produced by oral ingestion of air,
activities of the inhabitant bacteria organisms, and in some cases,
other
gastrointestinal diseases associated with gas production. The most
important intestinal gases identified and isolated within the gut lumen
have
been reported to include; nitrogen, hydrogen, methane, oxygen and carbon
di oxide. Intestinal gas accumulation and subsequent explosions
has been implicated as the culprit in several colonic surgical
complications. The hyper production of Hydrogen in response to certain
sugars
like lactose may be considered the expression of intolerance or a sugar mal digestion, with an abnormal fermentation by gut microbiota. An
enhanced understanding of the pathophysiological intricacies involved in
the production of intestinal gases is essential for the advancement of
present strategies utilized in the remediation of diseases associated
with intestinal gas production and accumulation.
#Pathophysiological Mechanism of #Intestinal Gas Production by Akefe I O in BJSTR
