Journals on Biomedical Science - BJSTR Journal

Abstract

Dandruff and underarm #malodor are caused by microorganisms. Personal hygiene products containing various types of antimicrobial agents are used to relieve this condition, but the effect is not long-lasting. In this study, we tried to maintain the antimicrobial effect for a long time by covalently binding the antimicrobial component to the hair shaft. #Antimicrobial activity against dandruff strains, underarm malodor associated bacteria, and skin microbial strains were evaluated using hair fixed with antimicrobial agents. The hair shaft covalently bonded of the QAC showed antibacterial activity against all tested bacteria. Although the #antibacterial effect was slightly decreased after 5 washes, it was confirmed that the antibacterial effect still remained. The results of this study may be applied to personal hygiene products such as shampoos and deodorants that act as antimicrobial agents to prevent and alleviate dandruff and axillary odor.Dandruff is the most common scalp condition that is often accompanied by itching and #erythema [1]. The complex causes of dandruff include excess sebum secretion from the sebaceous glands, hormonal imbalance, and excessive proliferation of #Malassezia species in the scalp. The viable numbers of these yeasts reportedly increase 1.5-2-fold in numbers when dandruff is present [2].

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Long-lasting Antimicrobial Effect Achieved via Immobilization of Antimicrobial Agents on Hair Shaft by Seong kil Son in BJSTR