Accuracy of Fnac in Diagnosing Thyroid Nodules: A Single Institution Experience by Ajay Kumar B in BJSTR
Abstract
Background: FNA is the first-line investigation in the diagnosis of thyroid nodules.
Aims: To determine the accuracy of FNAC in diagnosing thyroid nodules.
To identify the major cause of discrepancy in FNAC reports
Methods: The final histopathology report (HPR) of all
thyroidectomies done from January 2008 to December 2010 was retrieved by
a
retrospective search in institutional databases. Corresponding FNAC
reports were also retrieved. The correlation between FNAC and final
histopathology was studied to determine the accuracy with which FNAC
diagnosed thyroid disorders.
Results: The sensitivity and specificity of FNAC in diagnosing benign nodules is 92% and71.6% respectively.
A. The sensitivity and specificity of FNAC for diagnosis of neoplasm is 81.6% and 92% respectively.
B. The sensitivity and specificity of FNAC for diagnosis of malignancy is 87.8% and 98.2% respectively.
Conclusion: FNA is highly sensitive and specific in the diagnosis of thyroid nodules. Cytological similarities between hyperplasic nodule
and follicular neoplasm are a major source of error.
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