The Master Code of Biology: from Prions and Prions-like Invariants to the Self-assembly Thesis by Jean-Claude Perez in BJSTR
Abstract
For more than 25 years, we have been looking for biomathematical laws
controlling and structuring DNA, genes, proteins, chromosomes
and genomes [1,2]. In 1997 we discovered a simple numerical law based
solely on atomic masses, unifying the 3 languages of biology: DNA,
RNA, and amino acids. This law, “The Master Code Of Biology” is
published in 2009 in the book codex biogenesis [3] and then in 2015 in a
reference article peer review [4]. In 2017 we publish different
applications: HIV, SNPs, brain genetics [5-8]. On the other hand, at the
beginning
of the 2000s we studied the integrity of the Prions proteins (CJD,
Creutzfeldt-Jakob disease), showing a common invariant bi-attractors in
“W”,
while the amyloid was characterized by a pattern in “V” shape. Since
that time, biologists such as Claudio Soto have visually demonstrated in
3D
the same biological form in horseshoe for the amyloid protein [9-13].
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