Flavanoids from Saraca asoca- Ideal Medication for #Breast Cancer: A Molecular Simulation Approach by Sherin DR in BJSTR
Abstract
Breast cancer is one of the major causes of mortality in women. The
estrogen receptor becomes positive in such patients. Many of the
currently available anti breast cancer drugs produces severe side
effects. It demands natural products with low toxicity to fight against
estrogen
receptor. In this point, we tried to establish antiestrogen potential of
some natural flavonoids from the bark of Saraca asoca. The
vitality of these
drugs is well described in terms of pharmacokinetic parameters and
molecular orbital analysis. In the light of molecular simulation studies
we
reports a set of lead compounds having natural origin in the treatment
of breast cancer.
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