Monday, September 3, 2018

Segmental Resection of Duodenal Adenocarcinoma: Case Report by Faris Dawood Alaswad in BJSTR

Abstract

Primary malignant tumors of the duodenum represent 0.3% of all Castro-intestinal tract tumors but up to 50% of small bowel malignancies. Primary malignant tumors of the duodenum must be differentiated from malignant tumors of the ampulla, pancreas and common bile duct. The most frequent tumor of the duodenum is Adenocarcinoma [1,2]. Other primary tumors are lymphomas, leiomyosarcomas, carcinoid tumors, gastrinomas, and stromal tumors. Adenocarcinoma of the duodenum may arise from duodenal polyps observed in familial polyposis or Gardener’s syndrome, or be associated with celiac disease [3,4]. The tumor can be located in any part of the duodenum but the most frequent location is the second part. Malignant tumors of the duodenum are observed with the same frequency in men and women. The peak of frequency is the sixth decade, although the disease may develop in younger patients. Signs and symptoms are non specific. The main symptoms are: abdominal pain (15 to 60% of patients), weight loss (30 to 59%), nausea and vomiting (25 to 30%), jaundice (20 to 30%), hemorrhage (10 to 38%). A palpable abdominal mass is found in less than 5% of the patients [5].



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