#Silica Chloride Catalyzed Efficient Synthesis of #2,3-Dihydroquinazoline-4(1h)-Ones Derivatives In Water by Milind Ubale in BJSTR
Abstract
Describe method consist of eco-friendly procedure for the preparation
of 2,3-dihydroquinazoline-4(1H)-ones from equimolar
2-aminobenzamide and substituted aromatic aldehydes in presence of
20mol% of silica chloride. Green impact of reaction significantly
enhanced due to use of water as solvent and recyclable silica-chloride
as catalyst. Good to excellent yield of products, simple working
strategy
and easy purification are the advantage of present methodology
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