Abstract
Three types of #tissue-engineered products were developed using cell,
growth factor, and #biomaterial. The first product is a CDS composed
of allogeneic fibroblasts combined with a HA and Col spongy sheet. #Fibroblast can release various growth factors that are essential for
wound
healing. HA and Col have a potential to enhance #woundhealing. This CDS
can be #cryopreserved for a long period of up to clinical use. The
clinical
study demonstated that #allogeneic CDS is a useful product. The second
product is a wound dressing composed of HA and Col containing EGF.
EGF has a #potential to enhace wound healing. This wound dressing is a
freeze-dried spongy sheet, thereby the efficacy of EGF can be kept for
a long period of up to clinical use. The clinical study showed that
EGF-incorporating wound dressing is a practical product. The third
product
is an anti-adhesive #spongysheet composed of HA and Col containing EGF.
This is also a #freeze-driedspongy sheet. The animal study indicated
that EGF-incorporating anti-adhesive spongy sheet is a promissing
product.
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