Abstract
#Hepatocellular #carcinoma (HCC) is the fifth most common cancer and
the leading cause of cancer death in the world. Its poor prognosis
is mainly due to the late detection of the tumor, thus multiple genetic
markers including micro #RNAs are under research to improve detection
and prognosis of HCC.
Aim: of this study was to evaluate the diagnostic potential of
a panel of two circulating miR 143 and miR-550a as diagnostic
#biomarkers for hepatocellular carcinoma (HCC) among patients with hepatitis C virus
(HCV) infected Egyptian.
Methods: A total of 81 participants were included in this study (3 controls, 41 hepatitis C patients and 37 HCC patients). Samples were
collected, and both miR143 and miR-550a were assessed.
Efficacy of Plasma microRNA-143 and microRNA-550a as Potential Diagnostic and Prognostic Biomarkers for Chronic Hepatitis and Hepatocellular Carcinoma in Egyptian Patients by Sarah El-Nakeep in BJSTR
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