#Thalassemias are a heterogeneous group of genetic disorders
that result from a reduced rate of synthesis of or ß chains. The
genetic defects of hemoglobin are the most genetic disorders
worldwide. They occur in tropical and subtropical areas and most
appear to have been selected because the carrier state affords some
protection against malaria. Indonesia is among a group of countries
with high prevalence of thalassemias. The burden of this disorder in
the country is of such a magnitude that it represents a major public
health concern. Laboratory diagnosis of thalassemia, which consists
of blood film examinations and hemoglobin #electrophoresis, are the
most common modalities in our country since DNA analysis for
or ß #globin mutations is high cost and only available in the capital
city. On the other hand, diagnosis of thalassemia becomes more
complicated because of high prevalence of iron deficiency anemia in
the country [1].
For more Biomedical open access journals please click on
Challenges in Early Infant Diagnosis of Beta Thalassemias by Tika Adilistya in BJSTR
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