Wednesday, November 21, 2018

Role of FDG PET-CT in Distinction of Benign Thrombus and Tumor #Thrombus in #OncologicalPatients by Pelin Ozcan Kara in BJSTR

Abstract

Aim: Accurate diagnosis of tumor thrombus and distinguishing benignthrombus from tumor thrombus avoid unnecessary anticoagulant treatment of #oncologicalpatients and it is important for patient management. In this retrospective study, we aimed to demonstrate the role of FDG-PET/CT imaging for distinction of benign thrombus from tumor #thrombus.
Materials and Methods:FDG-PET/CT imaging performed for staging, restaging and treatment response in oncological patients with thrombus were evaluated for accurate diagnosis of tumor thrombus and distinguishing benign thrombus from tumor thrombus by the examination of maximum standard uptake value (SUVmax). PET-CT imaging were evaluated both with #visualassessment and increased metabolic activity. PET-CT findings were confirmed by clinical, radiological follow-up and biopsy in some cases.
Results:PET-CT imaging findings of a total of 37 patients with suspected tumor thrombus (25 men, 12 women, mean age: 53.62-range: 8-82) were evaluated, retrospectively. Tumor thrombus in 11 segments in 8 patients (9 linear, 2 focal) and benign thrombus in 45 regions in the other 29 patients were reported in the evaluation of a total of 56 thrombi region in 37 patients on visual analysis and according to the increased metabolic activity. The most common region of thrombosis was defined as vena cava inferior. SUVmax values ranged from 7.91 to 20 (mean: 12.8) in 8 tumor thrombus patients. Compared to #mediastinalregion increased #metabolicactivity was not detected in none of the 29 patients with benign thrombus and these patients were treated with #anticoagulant agents.

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