Abstract
#MagneticResonanceImaging (MRI) is indicated during
pregnancy for both #foetalpathology (CNS abnormalities, neck and
oropharynx masses, diaphragmatic hernia, placental pathology,
abdominal masses or intestinal pathology without sufficient
characterization at ultrasound, suspected foetal infection) and
maternal pathology (acute #abdomen, #appendicitis) [1,2]. The
developing human foetus is considered particularly vulnerable to
external insults, so that the possible consequences of MRI during
pregnancy have been widely investigated to isolate possible side
effects and identify the best safety parameters. The anatomy of
the human foetus changes every week of #gestation, affecting the
interactions with the external environment. The development of
the internal organs which are deputed to distribute and excrete
chemicals (e.g.) strongly affects the #pharmacokinetics of contrast
agents. The main foetal risks during MR examinations include GBCArelated
effects (#nephrogenicsystem #fibrosis - NSF -, #teratogenicity,
brain deposit) and #physicaleffects (body temperature increase,
acoustic injuries related to the scanner noise).
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For more Biomedical Research Articles on BJSTR
#MRI and Pregnancy by Pasquini L in BJSTR
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