PD-1/PD-L1 Checkpoint in Breast Implant-Associated #Anaplastic Large Cell #Lymphoma: A Case Report by Antonella Bianchi in BJSTR

Abstract

#Breastimplant-associated anaplastic large cell lymphoma (BI-ALCL) is a rare form of #malignancy that arises around mammary implants in patients undergoing #prostheticsurgery. It has been included as a provisional entity in the revised WHO classification of #lymphoidmalignancy. The PD-1/PD-L1 axis is one of the major mechanisms of #immune escaping exerted by several cancer types in which up-regulation of PD-L1 is observed. We report the presence of PD-1/PD-L1 checkpoint in a case of BI-ALCL of a 67 year old woman, whom previously had undergone mastectomy and reconstruction for breast #carcinoma.

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PD-1/PD-L1 Checkpoint in Breast Implant-Associated #Anaplastic Large Cell #Lymphoma: A Case Report by Antonella Bianchi in BJSTR