The Effects of the Combined Use of #Platelet-Rich Plasma and Xenograft on Alveolar Socket #Healing by Tonino Traini in BJSTR

Abstract

Objectives: The combination of #platelet-richplasma (PRP) with #anorganicbovinebone (ABB) has prospective values for the alveolar bone ridge preservation. The aim of this study was to evaluate the influence of PRP combined with ABB to improve the alveolar #sockethealing.

Materials and Methods: Ten post-extractions alveolar sockets were filled with ABB particles mixed with PRP gel and covered with a PRP clot membrane. After 4 months of healing, biopsies were collected from the implant beds sites for #histomorphometricanalysis. Newly formed bone (NFB), marrow spaces (MS), residual graft (RG) bone regenerative index (Br) and structural density index (Ds) were measured and compared to those published in #dental literature selected by PICOT method.

Results: In the present study, NFB was 26.5%, MS was 45.6% and RG was 24.5% while, using ABB plus #salinesolution and collagen membrane Vance et al. reported 26% of NFB, 54% of MS and 16% of RG. The difference was not significant (p> .05). Conversely, the Br indexes were 2.12 ±0.1(our study), 1.89±0.10 (by Vance) while the Ds indexes were 2.7±0.11 (our study), 2.3±0.12 (by Vance). The differences were significant (P=<.001).

Conclusion: The ABB-PRP was useful in alveolar socket preservation, demonstrating a significant increase of bone regenerative index and structural bone density.

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The Effects of the Combined Use of #Platelet-Rich Plasma and Xenograft on Alveolar Socket #Healing by Tonino Traini in BJSTR