Tuesday, December 11, 2018

Understanding the Detection of Shiga Toxin Producing #EscherichiaColi: Virulence Factors, Pathogenicity Islands or #Serotypes? by Colello, Rocio in BJSTR

Abstract

Shiga toxin-producing #Escherichiacoli (STEC) are important food borne #pathogens that can cause severe disease in children by producing two toxins (Stx1 and Stx2). This bacteria harbor several additional #virulence factorsand have been classified in different #serotypes that have been used as screening for detection of STEC. Aa is not possible to define when a STEC strain is pathogenic, it is important incorporate the risk assessment. Shiga toxin-producing Escherichia coli (STEC) are important food borne pathogens that can cause severe disease in children, including a life-threatening complication such as bloody diarrhea and hemolytic uremic #syndrome (HUS) [1]. The damage is produced by Shigatoxins encoded by stx1 and stx2 genes carried by #lysogenicphages that infect the bacteria [2]. STEC must intimately adhere to epithelial cells through #adhesions for deliver toxins efficiently to host organism.

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