Enoxaparin in Suspected #Heparin Induced #Thrombocytopenia: An Observational Follow-Up in Critically Ill Patients by Mohammad Taghi Beigmohammadi in BJSTR

Abstract

Background: HIT is over diagnosed in ICU patients and this leads to inappropriate use of direct agents and #bleeding. In this observational study safety use of #enoxaparine in critically ill patients with high probable HIT has been evaluated. Materials and Methods: In observational study, out of 564 patients admitted to the ICUs during 2012-2014, 88 patients with suspected HIT based on the clinical criteria (4Ts score) received either enoxaparin (n=48) or no treatment as control group (n=40). All of the patients had normal platelet count at hospital admission developed #thrombocytopenia (plt<100000/μl).The patients were followed for 5 days for any evidence of #thromboemboli, bleeding, petechiae, #cutaneousnecrosis. Doppler ultrasound of the lower limbs was performed as indicated and the peripheral blood smear was obtained for detection of #plateletaggregation. A p value less than 0.05 was considered statistically significant.

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Enoxaparin in Suspected #Heparin Induced #Thrombocytopenia: An Observational Follow-Up in Critically Ill Patients by Mohammad Taghi Beigmohammadi in BJSTR