Topical Administration of Autologous Prothrombin at Sites of Bone Allografts Might be Helpful in Promoting Bone Healing after #BoneAllograft Transplantation by Quanyi Guo in BJSTR

Abstract

Most of prothrombin initially located within #allograftbone matrix is removed or destroyed by deep-freezing, freeze-drying and gamma irradiation. Prothrombin is an inactive precursor to thrombin, a key factor which can promote bone healing. Therefore, we #hypothesis that #topicaladministration of autologous #prothrombin at sites of bone allografts might be helpful in promoting bone healing after #boneallograft transplantation and suggest appropriate amount of venous blood be harvested to concentrate autologous prothrombin before bone allograft #transplantation.

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Topical Administration of Autologous Prothrombin at Sites of Bone Allografts Might be Helpful in Promoting Bone Healing after #BoneAllograft Transplantation by Quanyi Guo in BJSTR