Biomedical Journal Articles

Abstract

#Hepatitis C virus (HCV) infection is a major leading cause of chronic hepatitis, #livercirrhosis, and #hepatocellularcarcinoma (HCC). The recent development of new direct-acting antivirals (DAAs) that are highly effective and well-tolerated has facilitated the achievement of sustained virological response rates in more than 90% of patients with HCV infection, regardless of the stage of liver #fibrosis, and is expected to reduce the rate of progression to HCC or risk of waitlist dropout among #livertransplant candidates with HCC. However, several studies have raised concerns about the risk of HCC in HCV patients treated with interferon (IFN)-free DAA-based #therapy, although other studies have failed to obtain findings supporting these results. These conflicting results prompted us to search for further reliable studies to draw a conclusion about this pivotal issue.

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https://biomedres.us/abstracts/BJSTR.MS.ID.001106.php

https://biomedres.us/fulltexts/BJSTR.MS.ID.001106.php

The Risk of #HepatocellularCarcinoma is increased in Hepatitis C Virus Patients Treated with Interferonfree Direct-acting #Antiviral-based Therapy: True or False? by Ken Sato in BJSTR