Journals on Medical Science

Abstract

Introduction: Eradication rates of many therapeutic regimens for #Helicobacter pylori (H. pylori) infection are not yet satisfactorily, mainly due to bacterial #resistance to #antibiotics, and to a limited availability of antibiotics in children.

Materials and Methods: Fifty-three children with H. pylori infection were prospectively enrolled, characterized by clinic, endoscopic findings and antibiotic resistance and treated with sequential therapy (ST cohort); this cohort was compared with an historic cohort of 106 children treated with standard triple therapy (TT cohort). The eradication rate of the two treatments was obtained, based on antibiotic resistance towards amoxicillin (AMO), #metronidazole (MET), and #clarithromycin (CLA).

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Can Sequential Therapy Overcome #AntimicrobialResistance in Children with Helicobacter pylori Infection? by Federica Gaiani in BJSTR