Abstract
Activity of key #antioxidant enzymes plays a critical role in the
induction of #hyperglycemia related #tissue damage. Gum Arabic (GA) is
an edible, dried sticky exudate from #Acaciaseyal and Acacia Senegal and
is rich with non-viscous soluble fiber. It is commonly used in food
industry and pharmaceutical field as an emulsifier and preservative. It
has strong antioxidant properties, and used to reduce the experimental
#nephrotoxicity against #gentamicin, cisplatin and to ameliorate
#cardiotoxicity. However, the effects of GA on oxidative stress in liver
of type I
diabetic rats have not been reported. Whether GA can change oxidative
related genes expression in liver of type I diabetic rat remains less
clear.
In the present study, we used type I diabetic rat model to investigate
our hypothesis that supplementation of GA in drinking water may protect
liver by reducing oxidative damage.
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