Abstract
The #biomodulation and the #biostimulation of Low Level Laser Therapy
(LLLT) promote wound healing, dentine repairing processes and
stimulate the biological activity of human Periodontal Ligament Stem
Cells (HPDLSCs), human Dental Pulp Stem Cells (HDPSCs), human Bone
Marrow Stem Cells (HBMSCs) and human Adipose Stem Cells (HADSCs). The
aim of the study was to review the literature on the LLLT effects
on DPDLSCs, DDPSCs, DBMSCs and HADSCs. The electronic search was
performed collecting articles in the PubMed, Medline, #Scopus, Lilacs and
Google Scholar databases from January 1990 to January 2018. LLLT was
able to significantly increase HPDLSCs, HDPSCs, #HBMSCs and HADSCs
proliferation rate, stimulating 3osteogenic differentiation and opening
new possibilities in the tissue regeneration. However, the research
background on this topic showed high heterogeneity and the in vitro
studies cannot always mimic the in vivo conditions. Thus, further
clinical studies should be performed to determine the appropriate dose
of irradiation in different patients.
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