Abstract
The purpose of this study is to develop the optimal method for heart
decellularization using for tissue engineering. Several different
chemical methods have been studied for decellularized tissues including
heart. Nevertheless, there are not certain results about which
combination of these methods may provide the best #transplantable,
effective scaffolds. In this study, a new modified #decellularization
method
has been applied to heart including different concentrations of ionic
and non-ionic detergents. To observe decellularization results
#histologicalanalysis were performed. As a result, it was observed that chosen
detergent solutions at low percentile concentrations and in short time
duration showed efficient performance. Histological analysis indicated
that samples were nuclei free in all groups.
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