Abstract
A significant body of evidence supports the notion that higher
levels of serum phosphate are associated with poor survival [1-3].
Similar outcome data have been reported in end stage #renaldisease
(ESRD) as well as individuals with various degree of renal function
impairment [1-3]. However, the lack of randomized clinical trial
(RCT) and a certain degree of heterogeneity among different studies
in this domain preclude the definition of what is the optimal
range of serum phosphate to target in different chronic kidney disease
(CKD) stages [1-3]. Phosphorus is an essential element for life.
It is a key factor in #energymetabolism being a fundamental constituent
of #adenosinetriphosphate (ATP) [2]. Similarly, phosphate
is a core element of #deoxyribonucleicacid (DNA) as well as a #cellmembranes.
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Phosphate Control in #ChronicKidneyDisease: an Unresolved Issue by Antonio Bellasi in BJSTR
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