Abstract
#Osteoarthritis is a degenerative disease of #joints and leading cause
of joint pain resulting from #subchondralbone hypertrophy and
#inflammation. Although, many researches have been focused to overcome
the articular cartilage, the latter has proven to be a very difficult
tissue
to repair defeating researchers, surgeons, and patients. Numerous
surgical techniques have been developed to address focal cartilage
defects.
One area that seems encouraging is cell-based therapies based on stem
cells to promote #cartilage repair. Several human body tissues contain
#mesenchymalstemcells from where these can be harvested and cultured.
This review summarises autologous #chondrocytesimplantation, first
generation, second generation, third generation and recent clinical
trials on mesenchymal stem cells implantation.
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For more Medical Case Reports Articles on BJSTR
Concise Review: Knee Cartilage Repair Techniques using Cellular Therapy by Hechmi Toumi in BJSTR
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