Abstract
#Bladder pain syndrome (BPS) is a chronic inflammatory status
of the bladder wall with no known cause. Patients with BPS suffer
from pain, pressure or inconvenience associated with the urinary
bladder. Furthermore, urgency (increased feeling to urinate) or an
increased frequency of #micturition both during the day as well as
during the night, has to be present [1]. Several studies have suggested
an #impairedbarrierfunction, leading to increased bladder wall
permeability of the #urothelium as a likely cause for this disabling
condition. In the healthy situation the bladder wall is impermeable
to any substances within the urine.
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