Abstract
Aim: The paper reorganized new findings in the field of #osteoblastogenesis and osteoclastogenesis for clinicians to identify
systemic and
local risks of oral and #maxillofacialosteogenicconditions (OMOCs) that
are not related to genetic diseases.
Method: The non-systemic review was undertaken by searching pertinent key wards in English literature. Case report and publications
with weak levels of evidence were excluded.
Results: Coupling factors from endocrine and #paracrinesystems affect osteoblastogenesis and #osteoclastogenesis in different
pathways.
Levels of hormones change with age or by medical conditions. Cytokine
accumulations are triggered by the local mechanical force or ischemia.
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