Thursday, April 18, 2019

Journals on Medical Research

Abstract

West syndrome is a rare and severe infant #epilepticencephalopathy, covering 25-30% of infantile #epilepsies. It’s incidence is 2-3.5/ 10000 live births. The clinical picture usually starts with infantile spasms, which can occur in clusters and is often associated with developmental arrest or regression. In 75% of the cases the interictal EEG shows #hypsarrhythmia, which is chaotic, high amplitude, slow wave activity. The underlying diseases can be a variety of different neurological etiologies, such as metabolic, structural developmental, perinatal lesions, genetic or #neurocutandisorders. Despite the widening scale of #diagnosticpossibilities, detection of the underlying disease is unsuccessful in case of at least a quarter of the patients [1]. Early diagnosis and adequate therapy are key factors in achieving better outcomes [2].

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