Journal on Medical Genetics - BJSTR Journal

Abstract

Objectives: Evaluation of the probable association between #bone mineral density (BMD) and SOST gene single #nucleotide polymorphisms (SNPs) in #postmenopausal Turkish women.

Methods: This prospective, case- control study was carried out with 204 postmenopausal Turkish women. The population was divided into 2 groups with respect to their lumbar spine T score as follows: 126 #osteoporotic women with T score lower than -2.5 SD (OP group) and 78 non-osteoporotic women with T score higher than -1 SD (NOP group). Genotyping of 4 SNPs was performed using polymerase chain reaction-restriction fragment length polymorphism.

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Is there any Association between Postmenopausal Osteoporosis and Sclerostin Gene Single Nucleotide Polymorphisms in Turkish Women? by Derya Deveci in BJSTR