Journals on Biomedical Engineering - BJSTR Journal

Abstract

The #knee joint cartilage often suffers from defect and it causes serious #health problem. CD34+ stem cells cells have been studied to heal bone fracture however the cells has never been studied to repair cartilage. This study also focuses on the use of scaffold and growth factor affecting the healing of cartilage defect using CD34+ cells. This is the first study reporting #hyaline cartilage regeneration on #osteochondral defect with intra articular injection of human peripheral blood CD34+ (HPB CD34+) cellated on the trochlear region of Sprague Dawley (SD) rats. A total of 30 male SD rats were randomly divided into 3 groups; the control group received PBS, experimental group 1 received HPB CD34+ cells, and experimental group 2 received HPB CD34+cells, hyaluronic acid, and growth factors (TGF-ß1, IGF-1, FGF, fibronectin).

For more articles on BJSTR Journals please click here: https://biomedres.us/

For more Biomedical Engineering Articles on BJSTR

https://biomedres.us/abstracts/BJSTR.MS.ID.001436.php

https://biomedres.us/fulltexts/BJSTR.MS.ID.001436.php

Hyaline Cartilage Regeneration on Osteochondral defects by Intraarticular Injection of Human Peripheral Blood CD34+ Cells, Hyaluronic Acid and Growth Factor in a Rat Model by Basuki Supartono in BJSTR