Abstract
#Infectious diseases are a major cause of threat throughout the world
which may have concern with microorganisms, specifically bacteria.
Various antibiotics are synthesized and used against infectious diseases
to mimic the death rate. The #tetracyclines are a #broad spectrum antibiotics discovered as natural products with exclusive biological and
chemical properties against both gram-positive/negative bacteria. Many
of members of this family also possess some non-antibacterial properties
such as anti-inflammatory, #immunosuppressant and inhibition of lipase.
Various studies reveals structure activity relationship of the
tetracycline family, which shows the bioactivity, strength and
selectivity to #biological target, specifically depends upon modification
of lower and upper #peripheral zones of tetracycline skeleton.
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