Wednesday, June 12, 2019

Journals on Medical Research - BJSTR Journal

Abstract

Background and Aims: The #alpha-2-adrenergic mechanism has been explored for a long time in #anesthesiology. Clonidine belongs to this class and has some interesting characteristics for this specialty.
Contents: This article illustrates pharmacological aspects, mechanisms of action and clinical use of #clonidine in anesthesiology. Sedation, analgesia, lower incidence of nausea, opioid needs and adverse effects reduction are some of the beneficial effects of its use. Adverse effects are bradycardia and low blood pressure.
Conclusion: Clonidine reduces post-operative needs of opioid, pain intensity and nausea incidence. However, high risk of #perioperative low blood pressure and #bradycardia must be taken in consideration when deciding using this drug.

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