Physical Medicine and Rehabilitation - BJSTR Journal

Abstract

Background: #Primary cardiac tumors (PCT) in children are #rare disorders. Prenatal diagnosis is feasible. Most of them have favorable prognosis, but some still prove fatal.Objective: To define clinical outcome of benign PCT and the possible impact of prenatal diagnosis.

Methods: 14 cases were collected between December 2005 and August 201. We included patients with pre and #postnatal diagnosis, medically and surgically managed. Pre and postnatal examinations, surgical procedures, clinical information before and after surgery, #histological diagnoses were reviewed.

Results: Seventy-two percent of PCT were detected prenatally. Median follow-up time was 3,13 years. In the medical managed group, one had complete spontaneous regression, 3 had spontaneous reduction, 2 underwent efficacious Enviroximes treatment and one was lost to follow-up. 46% of cases needed surgery. In two infants, #perioperative support with V-A ECMO and iNO was necessary. Complete excision of the mass was possible in 5 cases. Rate of hospital death was 20%. All but one late survivors were symptom-free at last clinical assessment. Clinical relevant recurrence of mixoma occurred in one case.

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Clinical Outcome of Benign Cardiac Tumors in Infants During A 13 Years’ Experience: Impact of Prenatal Diagnosis by Giovanni Battista Luciani in BJSTR