Medical and Medicinal Journal - BJSTR Journal

Abstract

Background: The prevalence of #chronic hepatitis-B virus (HBV) is highly variable by region in the world. In chronic HBV, most of exacerbations are associated with the interaction of immune response to HBV and virus replication. All kinds of chemotherapy regimens potentially cause HBV replication.

Case Report: 58-year-old male patient, non-small cell lung adenocarcinoma was diagnosed. Adjuvant chemotherapy combination including #navelbine and #cisplatin was initiated for the patient. He admitted with the complaints of weakness and fatique after the one week of the second cure of chemotherapy. On physical examination, oral mucosa, sclera and skin were icteric. HBV-DNA level was measured as > 1000000000 (1 billion) IU/mL.

Conclusion: Clear benefit or harm of routine hepatitis B screening is controversial during the use of chemotherapy in solid #organ tumours. Especially in our country in which HBV prevalence is high, HBV infection screening have to be considered in patients scheduled to receive chemotherapy due to solid organ tumours in terms of HBV reactivation.

For more articles on BJSTR Journal please click on https://biomedres.us/

For more Medical and Medicinal Articles on BJSTR

https://biomedres.us/fulltexts/BJSTR.MS.ID.001551.php

Should Patients be Routinely Screened for Hepatitis B Serology before the Use of #Chemotherapy Due to Solid Organ Tumors? by Murat Pekgöz in BJSTR