Immunological Diseases - BJSTR Journal

Abstract

#Helicobacter pylori (H. pylori) infection is the most common #chronic bacterial infection worldwide and it plays a very important role in the #pathogenesis of peptic ulcer, gastric carcinoma, and lymphoid #tissue lymphoma. High reinfection rates after successful eradication treatments make the oral cavity a possible reservoir area for the survival of the bacterium. Therefore, the relationship between H. pylori and oral/gastric diseases is being investigated and has become a remarkable issue in recent years. In the oral cavity, H. pylori was first isolated from a dental plaque sample of a patient with gastric H. pylori in 1989. Investigation into the relationship of H. pylori with oral diseases has shown that oral H. pylori may cause halitosis, #glossitis, recurrent #aphthous stomatitis and dental caries. Hence, the aim of this review is to demonstrate the relationship between H pylori and oral diseases in the context of the previous/latest research. Helicobacter pylori (H. pylori) is a spiral-shaped, gram-negative, urease-producing and highly #pathogenic microaerophilic bacteria which causes development of highly serious gastrointestinal disorders and is mainly acquired in childhood [1-4]. Almost 50% of the global population is affected by the gastric H. pylori infection. The infection is more prevalent in developing countries in comparison to developed nations [5]. The prevalence of H. pylori infection mainly depends on age, geographic area and ethnicity [6].

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Oral Signs of Helicobacter Pylori- Review of Clinical Outcomes by Damla Aksit Bicak in BJSTR