Journals on Biomedical Imaging - BJSTR Journal

Abstract

Sleep deprivation can have serious consequences, including but not limited to decreased cognitive performance, work productivity, and immune function, and increased obesity risk. Macular #carotenoids (Lutein, zeaxanthin, and meso-zeaxanthin) increase macular pigment and may reduce photo-oxidative stress by blocking blue light and through antioxidant action. This study is to evaluate the effect of a dietary supplement containing lutein, #zeaxanthin and #meso-zeaxanthin supplementation for six months on sleep quality using the Pittsburg Sleep Quality Index (PSQI) questionnaire in healthy young adults exposed to daily use of electronic devices and outer side activities.This were a double-blind, #placebo-controlled randomized (DBPCR) study in 48 healthy young adults (Age 18-25 y, males and females, non- smokers, body mass index <27 kg/m2). Inclusion #criteria included a minimum of 4 h/d screen time exposure from electronic devices combined with 2-3 h outdoor activity. Subjects were randomly assigned to ingest daily either a placebo (PLA, safflower oil), or 24 mg L/ Zi (#Lutein and Zeaxanthin isomers, L/Zi; 20 mg L/4 mg Zi). Macular pigment optical density, serum #melatonin, serum lutein and zeaxanthin were analyzed, and sleep quality assessed using the using the Pittsburg Sleep Quality Index (PSQI) questionnaire. Total sleep scores and sleep subgroup scores at the beginning and the end of the study was recorded and compared between groups. Statistical significance set at p<0.05.

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Lutein and Zeaxanthin Isomers Effect on Sleep Quality: A Randomized Placebo-Controlled Trial by Vijaya Juturu in BJSTR