Journals on Medical Research - BJSTR Journal

Abstract

Random mutation and natural selection occur in a variety of different environments. Three of the most important factors which govern the rate at which this phenomenon occurs is whether there is competition between the different variants for the resources of the environment or not whether the replicator can do #recombination and whether the intensity of selection has an impact on the evolutionary trajectory. Two different experimental models of random mutation and natural selection are analyzed to determine the impact of competition on random mutation and natural selection. One experiment places the different variants in competition for the resources of the environment while the lineages are attempting to evolve to the selection pressure while the other experiment allows the lineages to grow without intense competition for the resources of the #environment while the different lineages are attempting to evolve to the selection pressure. The mathematics which governs either experiment is discussed, and the results correlated to the medical problem of the evolution of drug resistance. 

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Random Mutation and Natural Selection In Competitive and Non-Competitive Environments by Alan Kleinman in BJSTR