Journals on Neuro Imaging - BJSTR Journal

Abstract

#Glioblastomas tend to be morphologically diverse. Although rare, #pseudoepithelial components (adenoid or epithelioid) can be a diagnostic challenge. We describe a case of a 47-year-old female patient initially complaining of neck pain and dizziness. On neurological examination, an unsteady gait and memory disturbances were noted. MRI showed a contrast-enhancing lesion in the left temporal lobe without significant edema, suggesting the presence of cerebral metastasis. After complete resection of the tumor (as verified by early post-op MRI), the patient made an uneventful recovery. Based on extensive #histopathological analyses, the tumor was diagnosed as #epithelioid glioblastoma (E-GBM). Two months after concomitant radiation and chemotherapy, the patient developed severe neck pain, became dizzy and was confused. CSF examination confirmed tumor cells, and MRI of the spine showed diffuse dural contrast enhancement, suggesting extensive #leptomeningeal spread. The patient passed away four months after the initial diagnosis.

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Epithelioid Glioblastoma with Leptomeningeal Gliomatosis - Case Report and Review of the Literature by Walid Albanna in BJSTR

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