Abstract
Plants, since ancient times, have been used globally across the
civilizations as valuable, safe and natural agents of therapeutic,
industrial
and environmental utilities. From the inception of civilization, humans
have relied on plants for their basic necessities like food, shelter,
clothing, fuel and health. Of all the uses ascribed to the plants, the
curative abilities of plants play an inevitable part as plants sometimes
comprise sole source for healing ailments for some civilizations. Plants
have also been explored for population control (Annona squamosa)
is
reported to posses various medicinal effects like insecticidal,
antiovulatory and abortifacient. The present study therefore reports the
effect of
ethanolic effect of leaves, bark and seeds on the fructose level in
testis, vas deferens and seminal vesicles, sperm count and sperm
motility in
rats. A significant decrease (p<0.05) was observed in the level of
fructose in testis, vas deferens and seminal vesicle on exposure to the
ethanolic
extract of leaves, bark and seeds of plant (Annona squamosa) and a
significant (p<0.05) decrease in sperm count and motility was also
observed
in the rats exposed to the extracts of plant in comparison to control
rats. The decrease in fructose level, sperm count and motility was found
to
be time and dose dependent. Among the different parts of the plant,
leaves, bark and seeds the effects were in the order leaf < bark<
seed. The
study clearly indicates plant extracts have potential to inhibit male
fertility.
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