Proteomics - The Future of Periodontal Diagnostics by Nisha KJ in BJSTR
Abstract
Recent advances of proteomic meth¬odologies have opened new
opportunities to obtain relevant information on normal and abnormal
processes occurring in the human body. Identifying unique patterns of
protein expression, or biomarkers, associated with specific diseases is
one of the most promising areas of clinical proteomics. Advances in
proteomic technologies have enabled comprehensive profiling of protein
expression in cells, tissue, and body fluids. The use of proteins as
biomarkers for periodontal disease has been the focus of researchers
over
the last few years. Unfortunately, many single protein biomarkers have
proven to be unreliable. Developing new diagnostic tests that can
simultaneously analyze the expression of multiple proteins may enable
early detection, targeted preventive measures and individualized
therapeutic intervention of periodontal diseases. This review discusses
the main proteomic techniques and their potential applications in the
field of periodontal diagnostics.
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