The
Effect of Local Anesthesia (Lidocaine 2%) with Epinephrine (1:100,000)
On Blood Pressure Level of Hypertensive Patients Reported To a Tertiary
Care Hospital, Peshawar, Pakistan by Muhammad Ilyas in BJSTR
Abstract
Objective: The objective of the study was to evaluate the effect of local anesthesia (Lidocaine) with epinephrine (1:100000) on blood
pressure level and medicine used by hypertensive patients having Prehypertension, stage I and stage II hypertension.
Methodology: This randomized controlled trial study was
carried out in the department of Oral and Maxillofacial Surgery, Sardar
Begum
Dental College, Peshawar, Pakistan from February 2016 to August 2016. A
total of 88 male and female hypertensive patients were selected and
were divide into two groups through lottery method: Group A: Having 28
patients who receive 3 cartridges of Lidocaine 2% with epinephrine
(1:100,000).Group B: Having 22 patients who receive 3 cartridges of
lidocaine 2% without epinephrine (1:100,000). The blood pressure was
measured prior to injection, 5minutes after injection, during extraction
and after extraction of the tooth. Aspiration was carried out prior to
injecting the local anesthesia. Statistical analysis was performed using
SPSS 22. P ≤ 0.05 was considered as significant.
Results: No significant increase in SBP and decrease in DBP
were seen 5 minutes after injection, during extraction and after
extraction
of the tooth. The most commonly medicine taken by patients were
β-blockers n=42 (47.72%). Pearson correlation revealed that increasing
the duration of tooth extraction will decrease SBP (-.204) and DBP
(-.106). ANOVA showed that the increase or decrease in SBP and DBP
was statistically not significant (P=.698) between intergroup.
Chi-square statistics exhibit that hypertension is highly associated
with 40-49
years age group (X2=21.286, P=0.000). Regression analysis showed no
significant relationship between β-blockers and local anesthesia with
epinephrine 1:100,000.
Conclusion: Three cartridges of local anesthesia with epinephrine 1:100,000 have no significant effect on SBP and DBP in pre-hypertensive,
stage-I and stage-II patients
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