Abstract
Chronic inflammatory conditions like #RheumatoidArthritis (RA) causes
deposition of #Amyloid Associated (AA) in various tissues or organs
resulting in secondary or reactive systemic amyloidosis. We have
reported here a 58-year old lady, known case of RA since 17 years with
very
poor compliance to treatment who presented with #chronicdiarrhea since 2
months, on evaluation, upper GI #endoscopy and #biopsy revealed
positive for #serumamyloid associated on #innumohistochemistry staining,
suggestive of secondary systemic amyloiosis. Symptoms gradually
disappeared with the prompt institution disease modifying #anti-rheumaticdrugs (DMARDs). GI amyloidosis has been reported up to 60% of
the patients with secondary amyloidosis and must not be forgotten while
evaluating the cause for chronic diarrhea in a patient with #chronicinflammatorycondition like RA.
#GastrointestinalAmyloidosis Manifesting as Chronic Diarrhea in a Case of #RheumatoidArthritis – A Case Report by Shefali Khanna Sharma in BJSTR
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