Monday, October 15, 2018

#Glucagonoma #NeuroendocrineTumor with the Clue of Necrolytic Migratory Erythematous Rash: A Case Report by Masoud Khoshnia in BJSTR

Abstract

Background: #Necrolyticmigratoryerythema (NME) is most commonly a #paraneoplasticcondition. It is the dermatologic manifestation classically associated with glucagonoma pancreatic #neuroendocrinetumor. #Glucagonoma syndrome has been defined by the constellation of secreting tumor associated with overproduction by the α-cells in the #pancreaticislets of Langerhans, abnormally elevated blood level of glucagon, and skin findings of NME.
Objective: Although it is not common, all physicians must have it in mind and consult for further investigation not to miss out NME.
Methods and Results: We report a case of a middle-aged female seen in clinic with longstanding skin lesions suggestive of NME revealing glucagonoma. Complete resolution of the cutaneous and systemic features occurred after surgical removal of the #tumor.




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