Tuesday, November 27, 2018

#Angiogenesis Inhibitors for #CancerTherapy by Shaker A Mousa in BJSTR

Abstract

#Inhibition of #angiogenesis, which refers to blocking the vessel formation from pre-existing #blood vessels, has become an attractive target for cancer therapy. Tumors beyond 2-3 mm in size induce the sprouting of new #bloodvessels from the surrounding #vasculature (sprouting angiogenesis). Design and development of new angiogenesis inhibitors has been validated as a target in several tumor types. In this min-review, we will focus on the role of different anti-angiogenesis strategies and inhibitors in treatment of #cancer.

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