#NeonatalSepsis Past to Present by Santosh Kumar Kamalakannan in BJSTR

Abstract

#Neonatalsepsis is a clinical syndrome characterized by systemic signs of infection and #bacteremia in the neonatal period [1]. Neonatal sepsis is a major cause of #mortality and #neurodevelopmentalimpairment among #neonates. It contributes to nearly 30 % of neonatal deaths in developing countries [2]. Inherent factors like poorly developed innate #immunesystem, immature skin barrier, #mucosaldefense mechanisms and blood brain barrier contribute to the increased susceptibility of the neonates to infection .Early recognition and aggressive management plays a pivotal role in saving these neonates. Bacterial infections are the most common cause of septicemia in neonates but fungal and viral infections can occur in the setting of an extreme premature baby and by vertical #transmission from the mother.

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#NeonatalSepsis Past to Present by Santosh Kumar Kamalakannan in BJSTR