Abstract
Aurora-A is a #serine-threoninekinase found over expressed in cancers
and #demonstrated to be an oncogene. Since the #kinase regulates
cell cycle progression several #pharmaceutical companies were involved in
the identification of inhibitors to be used in cancer treatments. Many
of such inhibitors are now commercially available but none of them
succeeded any phase III clinical trials, yet. The concern here is,
whether
Aurora-A is still a good target or #biomarker?
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Aurora A and #cancer by Rennes University in BJSTR
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