Understanding the Connections between Inexact Newton-Krylov PDE-Constrained LDDMM and LDDMM via Geodesic Shooting and Efficient #Adjoint Calculation by Monica Hernandez in BJSTR

Abstract

The dissociation constants of some synthesized #tetrahydropyrimidine derivatives were determined #potentiometrically at ionic strength of 0.1 M in N, N-dimethyl formamide: water 60:40 (v/v)system at 303.15 K. It is observed that #dissociationconstant depends on the substituent groups present in the compounds.The acidic or basic strength of material can be highlighted by the dissociation constants. They are also known as acidity constant, ionization constant or formation constant.Dissociation constant is one of the important physicochemical parameter which provides critical information about drug properties such as solubility, #lipophilicity, #acidity [1], transport behaviour, bonding to receptors [2] and permeability [3]. 

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#Tetrahydropyrimidine Derivatives: A Potentiometric Study to Determine Dissociation Constant by Shipra Baluja in BJSTR